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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTSS
All Species:
20.91
Human Site:
Y262
Identified Species:
46
UniProt:
P25774
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25774
NP_004070.3
331
37496
Y262
R
H
P
S
F
F
L
Y
R
S
G
V
Y
Y
E
Chimpanzee
Pan troglodytes
XP_001171268
331
37376
Y262
L
H
P
S
F
F
L
Y
R
S
G
V
Y
Y
E
Rhesus Macaque
Macaca mulatta
NP_001027984
329
36923
S260
L
T
S
F
Q
F
Y
S
K
G
V
Y
Y
D
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O70370
340
38420
Y271
S
H
S
S
F
F
F
Y
K
S
G
V
Y
D
D
Rat
Rattus norvegicus
Q02765
330
36815
Y261
S
H
S
S
F
F
L
Y
Q
S
G
V
Y
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518002
618
66856
S549
L
S
S
F
Q
F
Y
S
K
G
V
Y
F
D
E
Chicken
Gallus gallus
Q90686
334
37200
S265
L
P
S
F
Q
F
Y
S
R
G
V
Y
Y
D
T
Frog
Xenopus laevis
NP_001086670
320
35636
Y251
T
R
P
T
F
F
L
Y
K
S
G
V
Y
S
D
Zebra Danio
Brachydanio rerio
NP_001017661
330
36275
Y261
T
R
P
Q
F
I
F
Y
R
S
G
V
Y
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95029
371
41582
E302
E
S
F
Q
F
Y
S
E
G
V
Y
N
E
P
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43297
462
50948
L281
A
G
G
R
A
F
Q
L
Y
D
S
G
I
F
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
55.5
N.A.
N.A.
71.7
73.4
N.A.
30.4
48.2
61
58.3
N.A.
43.9
N.A.
N.A.
N.A.
Protein Similarity:
100
99.4
71
N.A.
N.A.
84.1
83.3
N.A.
39.3
62.2
77
73.4
N.A.
57.4
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
20
N.A.
N.A.
60
66.6
N.A.
13.3
20
60
53.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
26.6
N.A.
N.A.
73.3
80
N.A.
26.6
20
80
60
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
0
0
0
55
46
% D
% Glu:
10
0
0
0
0
0
0
10
0
0
0
0
10
0
37
% E
% Phe:
0
0
10
28
64
82
19
0
0
0
0
0
10
10
0
% F
% Gly:
0
10
10
0
0
0
0
0
10
28
55
10
0
0
0
% G
% His:
0
37
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
37
0
0
0
0
0
0
% K
% Leu:
37
0
0
0
0
0
37
10
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
10
37
0
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
19
28
0
10
0
10
0
0
0
0
0
10
% Q
% Arg:
10
19
0
10
0
0
0
0
37
0
0
0
0
0
0
% R
% Ser:
19
19
46
37
0
0
10
28
0
55
10
0
0
10
0
% S
% Thr:
19
10
0
10
0
0
0
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
10
28
55
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
28
55
10
0
10
28
73
19
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _