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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMA1 All Species: 40.91
Human Site: S110 Identified Species: 60
UniProt: P25786 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P25786 NP_002777.1 263 29556 S110 L P V S R L V S L I G S K T Q
Chimpanzee Pan troglodytes XP_508298 366 40729 S213 L P V S R L V S L I G S K T Q
Rhesus Macaque Macaca mulatta XP_001089332 371 41236 S218 L P V S R L V S L I G S K T Q
Dog Lupus familis XP_534070 368 40381 S215 L P V S R L V S L I G S K T Q
Cat Felis silvestris
Mouse Mus musculus Q9R1P4 263 29528 S110 L P V S R L V S L I G S K T Q
Rat Rattus norvegicus P18420 263 29499 S110 L P V S R L V S L I G S K T Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521804 262 29423 S109 L P V S R L V S L I G S K T Q
Chicken Gallus gallus O42265 260 28907 S109 L P V S R L V S L I G S K T Q
Frog Xenopus laevis Q9PVY6 248 28018 Y110 T V E Y I T R Y I A S L K Q R
Zebra Danio Brachydanio rerio NP_001003427 262 29230 S110 L P V S R L V S L I G S K T Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P12881 279 31040 T110 Y P V S R L I T N L G N K M Q
Honey Bee Apis mellifera XP_625032 276 30908 A110 L P V S R L L A S L G N K L Q
Nematode Worm Caenorhab. elegans O44156 260 28292 E110 V P I K K L A E S M Q L K L Q
Sea Urchin Strong. purpuratus XP_789764 181 20266 Q60 S S E L S S H Q K K I I P I D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O23712 277 30391 V110 L P V G R L V V H L A D K A Q
Baker's Yeast Sacchar. cerevisiae P40302 234 25586 H110 L A V E R A G H L L C D K A Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.8 70.8 71.1 N.A. 98 97.7 N.A. 97.3 92.7 32.3 89.3 N.A. 51.6 63 53.9 58.1
Protein Similarity: 100 71.8 70.8 71.1 N.A. 99.6 99.6 N.A. 98 95.8 53.9 92.7 N.A. 71.3 80.4 70.3 64.6
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 6.6 100 N.A. 53.3 60 26.6 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 20 100 N.A. 80 86.6 53.3 0
Percent
Protein Identity: N.A. N.A. N.A. 47.2 48.6 N.A.
Protein Similarity: N.A. N.A. N.A. 65.7 62.7 N.A.
P-Site Identity: N.A. N.A. N.A. 53.3 40 N.A.
P-Site Similarity: N.A. N.A. N.A. 60 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 7 7 7 0 7 7 0 0 13 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 13 0 0 7 % D
% Glu: 0 0 13 7 0 0 0 7 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 7 0 0 7 0 0 0 69 0 0 0 0 % G
% His: 0 0 0 0 0 0 7 7 7 0 0 0 0 0 0 % H
% Ile: 0 0 7 0 7 0 7 0 7 57 7 7 0 7 0 % I
% Lys: 0 0 0 7 7 0 0 0 7 7 0 0 94 0 0 % K
% Leu: 75 0 0 7 0 82 7 0 63 25 0 13 0 13 0 % L
% Met: 0 0 0 0 0 0 0 0 0 7 0 0 0 7 0 % M
% Asn: 0 0 0 0 0 0 0 0 7 0 0 13 0 0 0 % N
% Pro: 0 82 0 0 0 0 0 0 0 0 0 0 7 0 0 % P
% Gln: 0 0 0 0 0 0 0 7 0 0 7 0 0 7 88 % Q
% Arg: 0 0 0 0 82 0 7 0 0 0 0 0 0 0 7 % R
% Ser: 7 7 0 69 7 7 0 57 13 0 7 57 0 0 0 % S
% Thr: 7 0 0 0 0 7 0 7 0 0 0 0 0 57 0 % T
% Val: 7 7 82 0 0 0 63 7 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 7 0 0 0 7 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _