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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMA1 All Species: 43.64
Human Site: T42 Identified Species: 64
UniProt: P25786 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P25786 NP_002777.1 263 29556 T42 T V G L K S K T H A V L V A L
Chimpanzee Pan troglodytes XP_508298 366 40729 T145 T V G L K S K T H A V L V A L
Rhesus Macaque Macaca mulatta XP_001089332 371 41236 T150 T V G L K S K T H A V L V A L
Dog Lupus familis XP_534070 368 40381 T147 T V G L K S K T H A V L V A L
Cat Felis silvestris
Mouse Mus musculus Q9R1P4 263 29528 T42 T V G L K S K T H A V L V A L
Rat Rattus norvegicus P18420 263 29499 T42 T V G L K S K T H A V L V A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521804 262 29423 A43 G L K S K T H A V L V A L K R
Chicken Gallus gallus O42265 260 28907 A43 G L K S K T H A V L V A L K R
Frog Xenopus laevis Q9PVY6 248 28018 V42 V R G K E I V V L G V E K K S
Zebra Danio Brachydanio rerio NP_001003427 262 29230 S42 T V G L K S H S H A V L V A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P12881 279 31040 D42 T V G L K N K D Y A V L V A L
Honey Bee Apis mellifera XP_625032 276 30908 T42 T V G L K N K T H A V L I A L
Nematode Worm Caenorhab. elegans O44156 260 28292 T42 T V G I K S E T H A V I V A L
Sea Urchin Strong. purpuratus XP_789764 181 20266
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O23712 277 30391 S42 A I G L R S R S H V V L A C V
Baker's Yeast Sacchar. cerevisiae P40302 234 25586 T42 T V G L R S N T H A V L V A L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.8 70.8 71.1 N.A. 98 97.7 N.A. 97.3 92.7 32.3 89.3 N.A. 51.6 63 53.9 58.1
Protein Similarity: 100 71.8 70.8 71.1 N.A. 99.6 99.6 N.A. 98 95.8 53.9 92.7 N.A. 71.3 80.4 70.3 64.6
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 13.3 13.3 13.3 86.6 N.A. 80 86.6 80 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 33.3 33.3 20 93.3 N.A. 93.3 100 100 0
Percent
Protein Identity: N.A. N.A. N.A. 47.2 48.6 N.A.
Protein Similarity: N.A. N.A. N.A. 65.7 62.7 N.A.
P-Site Identity: N.A. N.A. N.A. 40 86.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 93.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 0 0 0 0 13 0 69 0 13 7 69 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % C
% Asp: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 7 0 7 0 0 0 0 7 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 13 0 82 0 0 0 0 0 0 7 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 19 0 69 0 0 0 0 0 0 % H
% Ile: 0 7 0 7 0 7 0 0 0 0 0 7 7 0 0 % I
% Lys: 0 0 13 7 75 0 50 0 0 0 0 0 7 19 0 % K
% Leu: 0 13 0 69 0 0 0 0 7 13 0 69 13 0 69 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 13 7 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 7 0 0 13 0 7 0 0 0 0 0 0 0 13 % R
% Ser: 0 0 0 13 0 63 0 13 0 0 0 0 0 0 7 % S
% Thr: 69 0 0 0 0 13 0 57 0 0 0 0 0 0 0 % T
% Val: 7 69 0 0 0 0 7 7 13 7 94 0 63 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _