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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMA2 All Species: 32.12
Human Site: S149 Identified Species: 47.11
UniProt: P25787 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P25787 NP_002778.1 234 25899 S149 G R P Y L F Q S D P S G A Y F
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_856136 183 20122 Q102 Q Q Y Y L V Y Q E P I P T A Q
Cat Felis silvestris
Mouse Mus musculus P49722 234 25907 S149 G R P Y L F Q S D P S G A Y F
Rat Rattus norvegicus P17220 234 25908 S149 G R P Y L F Q S D P S G A Y F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506542 234 25889 S149 G R P Y L F Q S D P S G A Y F
Chicken Gallus gallus NP_001012878 234 25901 S149 G R P Y L F Q S D P S G A Y F
Frog Xenopus laevis P24495 234 25816 S149 G R P Y L F Q S D P S G A Y F
Zebra Danio Brachydanio rerio NP_001019612 234 25886 S149 D R P Y L F Q S D P S G A Y F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40301 234 25888 S149 D R P Y L Y Q S D P S G A Y F
Honey Bee Apis mellifera XP_393294 234 25782 C149 G K P C L Y Q C D P S G A Y F
Nematode Worm Caenorhab. elegans Q27488 231 25317 S150 L L F Q C D P S G A Y F A W K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002318902 235 25607 V149 K G P Q L Y Q V D P S G S Y F
Maize Zea mays NP_001132248 235 25846 V149 N G P Q L Y Q V D P S G S Y F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O23708 235 25683 V149 K G P Q L Y Q V D P S G S Y F
Baker's Yeast Sacchar. cerevisiae P23639 250 27143 V150 N G F S L Y Q V D P S G S Y F
Red Bread Mold Neurospora crassa Q8X077 249 26979 V149 G G P M L Y Q V D P S G S Y F
Conservation
Percent
Protein Identity: 100 N.A. N.A. 77.7 N.A. 99.1 99.5 N.A. 99.5 98.2 95.7 95.3 N.A. 77.7 81.6 64.9 N.A.
Protein Similarity: 100 N.A. N.A. 77.7 N.A. 100 100 N.A. 99.5 99.1 97.4 97.4 N.A. 89.3 89.3 79 N.A.
P-Site Identity: 100 N.A. N.A. 20 N.A. 100 100 N.A. 100 100 100 93.3 N.A. 86.6 73.3 13.3 N.A.
P-Site Similarity: 100 N.A. N.A. 33.3 N.A. 100 100 N.A. 100 100 100 93.3 N.A. 93.3 86.6 20 N.A.
Percent
Protein Identity: 65.1 65.5 N.A. 65.5 57.2 62.6
Protein Similarity: 81.2 81.2 N.A. 80.8 69.6 73.4
P-Site Identity: 60 60 N.A. 60 53.3 66.6
P-Site Similarity: 73.3 73.3 N.A. 73.3 66.6 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 7 0 0 63 7 0 % A
% Cys: 0 0 0 7 7 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 13 0 0 0 0 7 0 0 88 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % E
% Phe: 0 0 13 0 0 44 0 0 0 0 0 7 0 0 88 % F
% Gly: 50 32 0 0 0 0 0 0 7 0 0 88 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % I
% Lys: 13 7 0 0 0 0 0 0 0 0 0 0 0 0 7 % K
% Leu: 7 7 0 0 94 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 82 0 0 0 7 0 0 94 0 7 0 0 0 % P
% Gln: 7 7 0 25 0 0 88 7 0 0 0 0 0 0 7 % Q
% Arg: 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 7 0 0 0 57 0 0 88 0 32 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % T
% Val: 0 0 0 0 0 7 0 32 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % W
% Tyr: 0 0 7 57 0 44 7 0 0 0 7 0 0 88 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _