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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMA2 All Species: 47.27
Human Site: Y101 Identified Species: 69.33
UniProt: P25787 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P25787 NP_002778.1 234 25899 Y101 A Q Q Y Y L V Y Q E P I P T A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_856136 183 20122 S54 A T E K K Q K S I L Y D E R S
Cat Felis silvestris
Mouse Mus musculus P49722 234 25907 Y101 A Q Q Y Y L V Y Q E P I P T A
Rat Rattus norvegicus P17220 234 25908 Y101 A Q Q Y Y L V Y Q E P I P T A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506542 234 25889 Y101 A Q Q Y Y L V Y H E P I P T A
Chicken Gallus gallus NP_001012878 234 25901 Y101 A Q Q Y F L V Y H E P I P T A
Frog Xenopus laevis P24495 234 25816 Y101 A Q Q Y Y L V Y Q E P I P T A
Zebra Danio Brachydanio rerio NP_001019612 234 25886 Y101 A Q Q Y F L V Y Q E P I P T G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40301 234 25888 Y101 A Q T Y Y L T Y K E P I P V S
Honey Bee Apis mellifera XP_393294 234 25782 Y101 A Q Q Y Q L I Y Q E P I P T A
Nematode Worm Caenorhab. elegans Q27488 231 25317 P102 M M Y G E E M P T I Q L V T D
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002318902 235 25607 Y101 A E Q Y H R L Y K E P I P V T
Maize Zea mays NP_001132248 235 25846 Y101 A Q Q Y Y R L Y K E H I P V T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O23708 235 25683 Y101 A E Q Y L R L Y K E P I P V T
Baker's Yeast Sacchar. cerevisiae P23639 250 27143 G102 T S Y K R I Y G E Y P P T K L
Red Bread Mold Neurospora crassa Q8X077 249 26979 Y101 H T G Y K R I Y N E Y P P T R
Conservation
Percent
Protein Identity: 100 N.A. N.A. 77.7 N.A. 99.1 99.5 N.A. 99.5 98.2 95.7 95.3 N.A. 77.7 81.6 64.9 N.A.
Protein Similarity: 100 N.A. N.A. 77.7 N.A. 100 100 N.A. 99.5 99.1 97.4 97.4 N.A. 89.3 89.3 79 N.A.
P-Site Identity: 100 N.A. N.A. 6.6 N.A. 100 100 N.A. 93.3 86.6 100 86.6 N.A. 66.6 86.6 6.6 N.A.
P-Site Similarity: 100 N.A. N.A. 20 N.A. 100 100 N.A. 93.3 93.3 100 93.3 N.A. 80 93.3 20 N.A.
Percent
Protein Identity: 65.1 65.5 N.A. 65.5 57.2 62.6
Protein Similarity: 81.2 81.2 N.A. 80.8 69.6 73.4
P-Site Identity: 53.3 60 N.A. 53.3 6.6 33.3
P-Site Similarity: 80 73.3 N.A. 73.3 20 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 82 0 0 0 0 0 0 0 0 0 0 0 0 0 44 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 7 % D
% Glu: 0 13 7 0 7 7 0 0 7 82 0 0 7 0 0 % E
% Phe: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 7 7 0 0 0 7 0 0 0 0 0 0 7 % G
% His: 7 0 0 0 7 0 0 0 13 0 7 0 0 0 0 % H
% Ile: 0 0 0 0 0 7 13 0 7 7 0 75 0 0 0 % I
% Lys: 0 0 0 13 13 0 7 0 25 0 0 0 0 7 0 % K
% Leu: 0 0 0 0 7 57 19 0 0 7 0 7 0 0 7 % L
% Met: 7 7 0 0 0 0 7 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 7 0 0 75 13 82 0 0 % P
% Gln: 0 63 69 0 7 7 0 0 38 0 7 0 0 0 0 % Q
% Arg: 0 0 0 0 7 25 0 0 0 0 0 0 0 7 7 % R
% Ser: 0 7 0 0 0 0 0 7 0 0 0 0 0 0 13 % S
% Thr: 7 13 7 0 0 0 7 0 7 0 0 0 7 63 19 % T
% Val: 0 0 0 0 0 0 44 0 0 0 0 0 7 25 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 13 82 44 0 7 82 0 7 13 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _