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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMA3
All Species:
49.09
Human Site:
T221
Identified Species:
67.5
UniProt:
P25788
Number Species:
16
Phosphosite Substitution
Charge Score:
0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25788
NP_002779.1
255
28433
T221
L
S
W
V
G
E
L
T
N
G
R
H
E
I
V
Chimpanzee
Pan troglodytes
XP_001164624
254
28373
T220
L
S
W
V
G
E
L
T
N
G
R
H
E
I
V
Rhesus Macaque
Macaca mulatta
XP_001091430
229
25427
Y199
K
E
V
A
K
I
I
Y
I
V
H
D
E
V
K
Dog
Lupus familis
XP_537460
255
28429
T221
L
S
W
V
G
E
I
T
K
G
R
H
E
I
V
Cat
Felis silvestris
Mouse
Mus musculus
O70435
255
28387
T221
L
S
W
V
G
E
L
T
K
G
R
H
E
I
V
Rat
Rattus norvegicus
P18422
255
28401
T221
L
S
W
V
G
E
L
T
K
G
R
H
E
I
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516758
255
28263
T221
P
S
W
P
R
A
L
T
K
G
R
H
E
I
V
Chicken
Gallus gallus
NP_001006491
255
28463
T221
L
S
W
V
G
E
I
T
N
G
K
H
E
I
V
Frog
Xenopus laevis
NP_001080243
255
28345
T221
L
S
W
V
G
K
I
T
N
G
K
H
E
I
V
Zebra Danio
Brachydanio rerio
NP_001025358
255
28391
T221
L
S
W
V
G
E
V
T
K
G
R
H
E
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V5C6
253
27657
T220
M
G
L
V
G
R
V
T
G
G
L
H
L
I
N
Honey Bee
Apis mellifera
XP_392518
254
27937
T220
M
S
W
V
G
K
H
T
N
G
K
H
E
R
I
Nematode Worm
Caenorhab. elegans
Q09583
250
27734
T220
M
G
W
V
G
E
Q
T
N
G
K
Y
E
E
V
Sea Urchin
Strong. purpuratus
XP_796247
259
28253
S225
L
S
W
V
G
K
V
S
N
G
R
H
E
L
V
Poplar Tree
Populus trichocarpa
XP_002299648
249
27365
E219
E
M
S
W
V
C
D
E
S
K
R
Q
H
E
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O23715
249
27359
E219
E
M
S
W
I
C
E
E
S
K
R
E
H
Q
K
Baker's Yeast
Sacchar. cerevisiae
P21242
288
31518
E223
I
S
W
C
S
L
S
E
T
N
G
L
H
K
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
86.6
99.2
N.A.
98.8
98.8
N.A.
85
96
91.3
88.6
N.A.
56.8
67
49
73.3
Protein Similarity:
100
99.2
87.8
99.6
N.A.
99.2
99.6
N.A.
89.4
99.2
98.4
98.4
N.A.
74.5
86.6
70.9
86.8
P-Site Identity:
100
100
6.6
86.6
N.A.
93.3
93.3
N.A.
66.6
86.6
80
80
N.A.
40
60
60
73.3
P-Site Similarity:
100
100
20
93.3
N.A.
93.3
93.3
N.A.
66.6
100
100
93.3
N.A.
53.3
86.6
80
100
Percent
Protein Identity:
62.3
N.A.
N.A.
60.3
45.4
N.A.
Protein Similarity:
76
N.A.
N.A.
74.9
62.8
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
6
0
6
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
6
0
12
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
6
0
0
0
0
6
0
0
0
% D
% Glu:
12
6
0
0
0
48
6
18
0
0
0
6
77
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% F
% Gly:
0
12
0
0
71
0
0
0
6
77
6
0
0
0
0
% G
% His:
0
0
0
0
0
0
6
0
0
0
6
71
18
0
0
% H
% Ile:
6
0
0
0
6
6
24
0
6
0
0
0
0
53
6
% I
% Lys:
6
0
0
0
6
18
0
0
30
12
24
0
0
6
18
% K
% Leu:
53
0
6
0
0
6
30
0
0
0
6
6
6
12
0
% L
% Met:
18
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
42
6
0
0
0
0
6
% N
% Pro:
6
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
6
0
0
0
0
6
0
6
0
% Q
% Arg:
0
0
0
0
6
6
0
0
0
0
59
0
0
6
0
% R
% Ser:
0
71
12
0
6
0
6
6
12
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
71
6
0
0
0
0
0
0
% T
% Val:
0
0
6
71
6
0
18
0
0
6
0
0
0
6
65
% V
% Trp:
0
0
77
12
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
6
0
0
0
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _