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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMA3 All Species: 37.88
Human Site: Y105 Identified Species: 52.08
UniProt: P25788 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P25788 NP_002779.1 255 28433 Y105 N F R S N F G Y N I P L K H L
Chimpanzee Pan troglodytes XP_001164624 254 28373 Y105 N F R S N F G Y N I P L K H L
Rhesus Macaque Macaca mulatta XP_001091430 229 25427 D84 A V A G L L A D A R S L A D I
Dog Lupus familis XP_537460 255 28429 Y105 N F R S N F G Y N I P L K H L
Cat Felis silvestris
Mouse Mus musculus O70435 255 28387 Y105 N F R S N F G Y N I P L K H L
Rat Rattus norvegicus P18422 255 28401 Y105 N F R S N F G Y N I P L K H L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516758 255 28263 Y105 N F R S N Y G Y N I P L K H L
Chicken Gallus gallus NP_001006491 255 28463 Y105 N F R T N Y G Y D I P L K H L
Frog Xenopus laevis NP_001080243 255 28345 Y105 N F R A N Y G Y D I P L K H L
Zebra Danio Brachydanio rerio NP_001025358 255 28391 H105 S F R S N Y G H D I P L K H L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V5C6 253 27657 Q105 N Y R Q Q F E Q A I P L K H L
Honey Bee Apis mellifera XP_392518 254 27937 I105 S Y K S Q Y G I G I P L K Y L
Nematode Worm Caenorhab. elegans Q09583 250 27734 R104 M K W L K D Y R E P M P I Q N
Sea Urchin Strong. purpuratus XP_796247 259 28253 T105 D Y R A S Y G T P I P V K H L
Poplar Tree Populus trichocarpa XP_002299648 249 27365 G104 T N Y Q S V Y G E P V P I K E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O23715 249 27359 G104 R S Y E S V Y G D A V P V K E
Baker's Yeast Sacchar. cerevisiae P21242 288 31518 T105 S F K K L Y K T P I P I P A F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 86.6 99.2 N.A. 98.8 98.8 N.A. 85 96 91.3 88.6 N.A. 56.8 67 49 73.3
Protein Similarity: 100 99.2 87.8 99.6 N.A. 99.2 99.6 N.A. 89.4 99.2 98.4 98.4 N.A. 74.5 86.6 70.9 86.8
P-Site Identity: 100 100 6.6 100 N.A. 100 100 N.A. 93.3 80 80 73.3 N.A. 60 46.6 0 46.6
P-Site Similarity: 100 100 13.3 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 66.6 80 0 86.6
Percent
Protein Identity: 62.3 N.A. N.A. 60.3 45.4 N.A.
Protein Similarity: 76 N.A. N.A. 74.9 62.8 N.A.
P-Site Identity: 0 N.A. N.A. 0 20 N.A.
P-Site Similarity: 6.6 N.A. N.A. 13.3 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 6 12 0 0 6 0 12 6 0 0 6 6 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 6 0 0 0 0 6 0 6 24 0 0 0 0 6 0 % D
% Glu: 0 0 0 6 0 0 6 0 12 0 0 0 0 0 12 % E
% Phe: 0 59 0 0 0 36 0 0 0 0 0 0 0 0 6 % F
% Gly: 0 0 0 6 0 0 65 12 6 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 6 0 0 0 0 0 65 0 % H
% Ile: 0 0 0 0 0 0 0 6 0 77 0 6 12 0 6 % I
% Lys: 0 6 12 6 6 0 6 0 0 0 0 0 71 12 0 % K
% Leu: 0 0 0 6 12 6 0 0 0 0 0 71 0 0 71 % L
% Met: 6 0 0 0 0 0 0 0 0 0 6 0 0 0 0 % M
% Asn: 53 6 0 0 53 0 0 0 36 0 0 0 0 0 6 % N
% Pro: 0 0 0 0 0 0 0 0 12 12 77 18 6 0 0 % P
% Gln: 0 0 0 12 12 0 0 6 0 0 0 0 0 6 0 % Q
% Arg: 6 0 65 0 0 0 0 6 0 6 0 0 0 0 0 % R
% Ser: 18 6 0 48 18 0 0 0 0 0 6 0 0 0 0 % S
% Thr: 6 0 0 6 0 0 0 12 0 0 0 0 0 0 0 % T
% Val: 0 6 0 0 0 12 0 0 0 0 12 6 6 0 0 % V
% Trp: 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 18 12 0 0 42 18 48 0 0 0 0 0 6 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _