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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PSMA4
All Species:
42.73
Human Site:
T223
Identified Species:
58.75
UniProt:
P25789
Number Species:
16
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25789
NP_001096137.1
261
29484
T223
L
T
R
E
N
G
K
T
V
I
R
V
L
K
Q
Chimpanzee
Pan troglodytes
XP_001150097
235
26721
E217
L
I
K
K
H
E
E
E
E
A
K
A
E
R
E
Rhesus Macaque
Macaca mulatta
XP_001108132
307
34615
T269
L
T
R
E
N
G
K
T
V
I
R
V
L
K
Q
Dog
Lupus familis
XP_532362
261
29465
T223
L
T
R
E
N
G
K
T
V
I
R
V
L
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9R1P0
261
29452
T223
L
T
R
E
S
G
K
T
V
I
R
V
L
K
Q
Rat
Rattus norvegicus
P21670
261
29479
T223
L
T
R
E
N
G
K
T
V
I
R
V
L
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511366
261
29395
T223
L
T
R
E
N
G
K
T
T
I
R
V
L
K
Q
Chicken
Gallus gallus
XP_413742
261
29479
T223
L
T
R
E
N
G
K
T
V
I
R
V
L
K
Q
Frog
Xenopus laevis
NP_001089811
261
29436
T223
L
T
R
E
N
G
K
T
K
I
R
V
L
K
Q
Zebra Danio
Brachydanio rerio
NP_999862
261
29314
T223
L
T
R
E
N
G
K
T
K
I
K
V
L
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18053
264
29393
D223
M
A
T
L
Q
R
V
D
N
K
T
V
Y
S
V
Honey Bee
Apis mellifera
XP_397196
507
57720
T473
L
T
R
E
N
G
K
T
I
T
R
I
L
P
M
Nematode Worm
Caenorhab. elegans
Q9N599
250
28264
E223
R
D
G
K
T
V
L
E
E
L
T
T
K
E
V
Sea Urchin
Strong. purpuratus
XP_786996
257
28714
T223
L
T
R
E
D
G
K
T
K
I
R
I
L
P
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001131770
250
26991
E223
F
L
Q
P
G
S
G
E
V
Q
Y
Q
V
C
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81148
250
27457
V223
Y
L
T
P
S
K
T
V
K
Y
H
V
H
S
P
Baker's Yeast
Sacchar. cerevisiae
P23638
258
28696
E224
R
K
G
A
N
D
G
E
V
Y
Q
K
I
F
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90
85
99.2
N.A.
98.8
99.2
N.A.
99.2
99.2
96.9
96.1
N.A.
70.8
39.8
65.1
78.5
Protein Similarity:
100
90
85
99.6
N.A.
100
100
N.A.
99.2
100
98.4
98.8
N.A.
83.3
45.5
79.3
90
P-Site Identity:
100
6.6
100
100
N.A.
93.3
100
N.A.
93.3
100
93.3
86.6
N.A.
6.6
66.6
0
66.6
P-Site Similarity:
100
53.3
100
100
N.A.
100
100
N.A.
93.3
100
93.3
93.3
N.A.
13.3
80
20
80
Percent
Protein Identity:
N.A.
60.1
N.A.
55.9
50.9
N.A.
Protein Similarity:
N.A.
72
N.A.
70.1
72
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
20
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
6
0
0
0
0
0
6
0
6
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% C
% Asp:
0
6
0
0
6
6
0
6
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
65
0
6
6
24
12
0
0
0
6
6
6
% E
% Phe:
6
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% F
% Gly:
0
0
12
0
6
65
12
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
6
0
0
0
0
0
6
0
6
0
0
% H
% Ile:
0
6
0
0
0
0
0
0
6
59
0
12
6
0
0
% I
% Lys:
0
6
6
12
0
6
65
0
24
6
12
6
6
53
6
% K
% Leu:
71
12
0
6
0
0
6
0
0
6
0
0
65
0
0
% L
% Met:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% M
% Asn:
0
0
0
0
59
0
0
0
6
0
0
0
0
0
0
% N
% Pro:
0
0
0
12
0
0
0
0
0
0
0
0
0
12
6
% P
% Gln:
0
0
6
0
6
0
0
0
0
6
6
6
0
0
53
% Q
% Arg:
12
0
65
0
0
6
0
0
0
0
59
0
0
6
0
% R
% Ser:
0
0
0
0
12
6
0
0
0
0
0
0
0
12
6
% S
% Thr:
0
65
12
0
6
0
6
65
6
6
12
6
0
0
0
% T
% Val:
0
0
0
0
0
6
6
6
48
0
0
65
6
0
18
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
0
0
0
0
0
0
0
12
6
0
6
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _