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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UCP1
All Species:
22.12
Human Site:
S250
Identified Species:
48.67
UniProt:
P25874
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25874
NP_068605.1
307
33005
S250
S
P
P
G
Q
Y
K
S
V
P
N
C
A
M
K
Chimpanzee
Pan troglodytes
XP_517450
307
32986
S250
S
P
P
G
Q
Y
K
S
V
P
N
C
A
M
K
Rhesus Macaque
Macaca mulatta
XP_001090457
307
33219
S250
S
P
P
G
Q
Y
R
S
V
P
N
C
A
M
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P12242
307
33229
S250
S
L
P
G
Q
Y
P
S
V
P
S
C
A
M
S
Rat
Rattus norvegicus
P04633
307
33193
S250
S
L
P
G
Q
Y
P
S
V
P
S
C
A
M
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512700
349
37751
S292
S
P
P
G
Q
Y
L
S
A
L
N
C
A
W
T
Chicken
Gallus gallus
NP_989438
307
33112
N253
A
S
P
G
Q
Y
R
N
V
P
S
C
L
L
A
Frog
Xenopus laevis
Q6GQ22
291
32540
A237
N
Q
R
S
I
R
D
A
S
N
S
S
Y
K
G
Zebra Danio
Brachydanio rerio
Q9W720
310
33554
S253
S
A
Q
G
Q
Y
S
S
A
L
N
C
A
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001185598
317
34608
N256
V
V
K
T
R
F
M
N
S
S
P
G
Q
Y
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06143
298
32973
P244
N
G
S
G
D
H
Q
P
A
L
K
I
L
A
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
95.4
N.A.
N.A.
79.1
79.1
N.A.
57.8
54.7
33.2
57
N.A.
N.A.
N.A.
N.A.
51.7
Protein Similarity:
100
99
98
N.A.
N.A.
88.5
88.5
N.A.
70.1
73.2
52.1
72.5
N.A.
N.A.
N.A.
N.A.
68.4
P-Site Identity:
100
100
93.3
N.A.
N.A.
73.3
73.3
N.A.
66.6
46.6
0
53.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
N.A.
N.A.
80
80
N.A.
66.6
80
20
60
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
0
0
10
28
0
0
0
64
10
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
73
0
0
0
% C
% Asp:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
82
0
0
0
0
0
0
0
10
0
0
10
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
0
10
0
0
0
19
0
0
0
10
0
0
10
28
% K
% Leu:
0
19
0
0
0
0
10
0
0
28
0
0
19
10
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
46
0
% M
% Asn:
19
0
0
0
0
0
0
19
0
10
46
0
0
0
0
% N
% Pro:
0
37
64
0
0
0
19
10
0
55
10
0
0
0
0
% P
% Gln:
0
10
10
0
73
0
10
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
10
0
10
10
19
0
0
0
0
0
0
0
10
% R
% Ser:
64
10
10
10
0
0
10
64
19
10
37
10
0
0
10
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
19
% T
% Val:
10
10
0
0
0
0
0
0
55
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
73
0
0
0
0
0
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _