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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NPY1R All Species: 29.09
Human Site: Y253 Identified Species: 58.18
UniProt: P25929 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P25929 NP_000900.1 384 44392 Y253 D K M R D N K Y R S S E T K R
Chimpanzee Pan troglodytes XP_001148035 383 44259 Y253 D K M R D N K Y R S S E T K R
Rhesus Macaque Macaca mulatta Q9GK74 381 42711 H258 S P G A A N D H Y H Q R R Q K
Dog Lupus familis XP_546199 375 42357 S255 F R K G T Y S S R A W Q M K R
Cat Felis silvestris
Mouse Mus musculus Q04573 382 43996 Y252 D K I R D S K Y R S S E T K R
Rat Rattus norvegicus P21555 382 44098 Y252 D K I R D S K Y R S S E T K R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508180 384 44525 Y253 D K M R D N K Y R S T E T K R
Chicken Gallus gallus Q9DDN6 385 43491 H262 S P G A G N D H Y H H R R Q K
Frog Xenopus laevis P34992 366 42234 Y248 D K I R D N K Y R S S E T K R
Zebra Danio Brachydanio rerio NP_001095861 380 42936 Y262 E R I R E N K Y R S S E S K R
Tiger Blowfish Takifugu rubipres NP_001098074 364 41001 K243 R G R N G A Q K R N R G S A R
Fruit Fly Dros. melanogaster P30975 519 58378 E314 E C T P R Q V E N V R S K R R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 28.9 44.2 N.A. 93.2 92.9 N.A. 92.1 29.6 75.7 56.2 47.1 22.5 N.A. N.A. N.A.
Protein Similarity: 100 99.7 49.7 65 N.A. 97.6 97.4 N.A. 96.8 50.3 84.1 75.2 66.4 41 N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 20 N.A. 86.6 86.6 N.A. 93.3 6.6 93.3 66.6 13.3 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 26.6 40 N.A. 100 100 N.A. 100 26.6 100 100 33.3 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 17 9 9 0 0 0 9 0 0 0 9 0 % A
% Cys: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 50 0 0 0 50 0 17 0 0 0 0 0 0 0 0 % D
% Glu: 17 0 0 0 9 0 0 9 0 0 0 59 0 0 0 % E
% Phe: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 17 9 17 0 0 0 0 0 0 9 0 0 0 % G
% His: 0 0 0 0 0 0 0 17 0 17 9 0 0 0 0 % H
% Ile: 0 0 34 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 50 9 0 0 0 59 9 0 0 0 0 9 67 17 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 25 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 0 0 0 9 0 59 0 0 9 9 0 0 0 0 0 % N
% Pro: 0 17 0 9 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 9 9 0 0 0 9 9 0 17 0 % Q
% Arg: 9 17 9 59 9 0 0 0 75 0 17 17 17 9 84 % R
% Ser: 17 0 0 0 0 17 9 9 0 59 50 9 17 0 0 % S
% Thr: 0 0 9 0 9 0 0 0 0 0 9 0 50 0 0 % T
% Val: 0 0 0 0 0 0 9 0 0 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 59 17 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _