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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NFKBIA
All Species:
30.61
Human Site:
Y42
Identified Species:
61.21
UniProt:
P25963
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P25963
NP_065390.1
317
35609
Y42
D
S
M
K
D
E
E
Y
E
Q
M
V
K
E
L
Chimpanzee
Pan troglodytes
XP_001168452
534
57746
N65
E
S
A
G
V
Q
D
N
L
F
L
E
K
A
M
Rhesus Macaque
Macaca mulatta
XP_001087842
317
35574
Y42
D
S
M
K
D
E
E
Y
E
Q
M
V
K
E
L
Dog
Lupus familis
XP_537413
515
57309
Y243
D
S
M
K
D
E
E
Y
E
Q
L
V
K
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1E3
314
35053
Y42
D
S
M
K
D
E
E
Y
E
Q
M
V
K
E
L
Rat
Rattus norvegicus
Q63746
314
34999
Y42
D
S
M
K
D
E
D
Y
E
Q
M
V
K
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519324
329
36001
Y46
D
S
M
K
D
E
D
Y
E
L
M
V
Q
E
L
Chicken
Gallus gallus
Q91974
318
35380
Y46
D
S
M
K
E
E
E
Y
R
Q
L
V
R
E
L
Frog
Xenopus laevis
NP_001086998
315
35926
Y43
D
S
L
K
E
D
E
Y
T
A
I
M
K
D
I
Zebra Danio
Brachydanio rerio
NP_955923
312
34594
L46
D
S
L
K
E
D
N
L
P
S
L
E
E
C
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q03017
500
53800
K130
E
D
Q
E
E
Q
E
K
E
E
E
H
Q
D
T
Honey Bee
Apis mellifera
NP_001157184
384
42622
Q18
S
D
V
P
E
N
E
Q
Q
K
S
E
K
Q
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.8
99.6
58
N.A.
91.1
90.8
N.A.
77.8
71.6
59.9
47.3
N.A.
23.7
30.9
N.A.
N.A.
Protein Similarity:
100
35.9
100
59.8
N.A.
94
94
N.A.
85.1
82
75.7
66.2
N.A.
37.2
48.4
N.A.
N.A.
P-Site Identity:
100
13.3
100
93.3
N.A.
100
93.3
N.A.
80
73.3
40
20
N.A.
13.3
13.3
N.A.
N.A.
P-Site Similarity:
100
46.6
100
100
N.A.
100
100
N.A.
93.3
93.3
86.6
53.3
N.A.
60
46.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
0
0
0
9
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
75
17
0
0
50
17
25
0
0
0
0
0
0
17
0
% D
% Glu:
17
0
0
9
42
59
67
0
59
9
9
25
9
59
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% I
% Lys:
0
0
0
75
0
0
0
9
0
9
0
0
67
0
0
% K
% Leu:
0
0
17
0
0
0
0
9
9
9
34
0
0
0
59
% L
% Met:
0
0
59
0
0
0
0
0
0
0
42
9
0
0
9
% M
% Asn:
0
0
0
0
0
9
9
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
9
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
0
17
0
9
9
50
0
0
17
9
0
% Q
% Arg:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
9
% R
% Ser:
9
84
0
0
0
0
0
0
0
9
9
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
9
% T
% Val:
0
0
9
0
9
0
0
0
0
0
0
59
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _