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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITGB8
All Species:
14.24
Human Site:
Y722
Identified Species:
28.48
UniProt:
P26012
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26012
NP_002205.1
769
85632
Y722
K
I
K
S
S
S
D
Y
R
V
S
A
S
K
K
Chimpanzee
Pan troglodytes
XP_518987
769
85642
Y722
K
I
K
S
S
S
D
Y
R
V
S
A
S
K
K
Rhesus Macaque
Macaca mulatta
XP_001103130
769
85509
Y722
K
I
K
S
S
S
D
Y
R
V
S
A
S
K
K
Dog
Lupus familis
XP_532487
767
85403
Y720
K
I
K
S
S
A
D
Y
R
V
S
A
S
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0T9
787
86023
K739
L
V
S
F
H
D
R
K
E
V
A
K
F
E
A
Rat
Rattus norvegicus
Q6AYF4
787
85940
R738
L
L
V
S
F
H
D
R
K
E
V
A
K
F
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515060
293
32446
K247
Q
S
H
I
G
W
R
K
E
A
K
R
L
L
L
Chicken
Gallus gallus
P07228
803
88535
I748
V
V
A
G
I
V
L
I
G
L
A
L
L
L
I
Frog
Xenopus laevis
P12607
798
88285
I743
V
V
A
G
I
V
L
I
G
L
A
L
L
L
I
Zebra Danio
Brachydanio rerio
XP_001919626
669
74858
T623
T
E
P
Q
F
E
H
T
H
K
D
S
S
Y
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P11584
846
92638
M782
V
F
M
L
G
I
V
M
G
V
I
A
A
I
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27874
809
90119
L743
V
P
V
L
A
I
V
L
G
V
I
A
G
I
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.9
91.8
N.A.
37
37
N.A.
31
35.2
34.4
38.4
N.A.
29.7
N.A.
30.1
N.A.
Protein Similarity:
100
99.8
99.4
95.5
N.A.
54.7
55.2
N.A.
34.8
50.9
52
54
N.A.
46.6
N.A.
49.2
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
6.6
20
N.A.
0
0
0
6.6
N.A.
13.3
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
26.6
40
N.A.
6.6
20
20
13.3
N.A.
20
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
9
9
0
0
0
9
25
59
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
42
0
0
0
9
0
0
0
0
% D
% Glu:
0
9
0
0
0
9
0
0
17
9
0
0
0
9
9
% E
% Phe:
0
9
0
9
17
0
0
0
0
0
0
0
9
9
0
% F
% Gly:
0
0
0
17
17
0
0
0
34
0
0
0
9
0
0
% G
% His:
0
0
9
0
9
9
9
0
9
0
0
0
0
0
0
% H
% Ile:
0
34
0
9
17
17
0
17
0
0
17
0
0
17
17
% I
% Lys:
34
0
34
0
0
0
0
17
9
9
9
9
9
34
34
% K
% Leu:
17
9
0
17
0
0
17
9
0
17
0
17
25
25
9
% L
% Met:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
17
9
34
0
0
9
0
0
0
% R
% Ser:
0
9
9
42
34
25
0
0
0
0
34
9
42
0
0
% S
% Thr:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% T
% Val:
34
25
17
0
0
17
17
0
0
59
9
0
0
0
25
% V
% Trp:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
34
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _