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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MSN All Species: 45.45
Human Site: S249 Identified Species: 100
UniProt: P26038 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P26038 NP_002435.1 577 67820 S249 W S E I R N I S F N D K K F V
Chimpanzee Pan troglodytes XP_522176 765 86955 S431 W S E I R N I S F N D K K F V
Rhesus Macaque Macaca mulatta XP_001100546 895 102426 S567 W S E I R N I S F N D K K F V
Dog Lupus familis XP_848336 577 67891 S249 W S E I R N I S F N D K K F V
Cat Felis silvestris
Mouse Mus musculus P26041 577 67748 S249 W S E I R N I S F N D K K F V
Rat Rattus norvegicus O35763 577 67720 S249 W S E I R N I S F N D K K F V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518902 711 80146 S386 W S E I R N I S F N D K K F V
Chicken Gallus gallus Q9PU45 583 68536 S249 W S E I R N I S F N D K K F V
Frog Xenopus laevis NP_001090034 580 68116 S249 W S E I R N I S F N D K K F V
Zebra Danio Brachydanio rerio NP_001004296 579 68015 S249 W S E I R N I S F N D K K F V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P46150 578 68123 S250 W S E I R N I S F S E K K F I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 61.9 64.4 98.7 N.A. 98.6 97.7 N.A. 68.9 81.3 87.5 84.2 N.A. 59.5 N.A. N.A. N.A.
Protein Similarity: 100 68.5 64.4 99.6 N.A. 99.4 98.7 N.A. 73 89.7 93.7 91.7 N.A. 75.7 N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 80 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 100 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 91 0 0 0 0 % D
% Glu: 0 0 100 0 0 0 0 0 0 0 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 100 0 0 0 0 100 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 100 0 0 100 0 0 0 0 0 0 0 10 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 100 100 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 100 0 0 0 91 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 100 0 0 0 0 0 100 0 10 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 91 % V
% Trp: 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _