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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX6
All Species:
27.27
Human Site:
S448
Identified Species:
40
UniProt:
P26196
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26196
NP_004388.2
483
54417
S448
D
D
R
F
N
L
K
S
I
E
E
Q
L
G
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536551
483
54384
S448
D
D
R
F
N
L
K
S
I
E
E
Q
L
G
T
Cat
Felis silvestris
Mouse
Mus musculus
P54823
483
54173
S448
D
D
R
F
N
L
K
S
I
E
E
Q
L
G
T
Rat
Rattus norvegicus
NP_001102762
483
54226
S448
D
D
R
F
N
L
K
S
I
E
E
Q
L
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516184
444
50248
S409
D
D
R
F
N
L
K
S
I
E
E
Q
L
G
T
Chicken
Gallus gallus
Q5ZKB9
483
54399
S448
D
D
R
F
N
L
K
S
I
E
E
Q
L
G
T
Frog
Xenopus laevis
P54824
481
54055
S447
D
D
R
F
N
L
K
S
I
E
E
Q
L
G
T
Zebra Danio
Brachydanio rerio
XP_684923
484
53892
G449
D
D
R
F
N
L
K
G
I
E
E
Q
L
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23128
459
51927
R409
E
D
R
F
D
L
H
R
I
E
K
E
L
G
T
Honey Bee
Apis mellifera
XP_624586
443
50482
R405
E
D
R
F
N
L
H
R
I
E
Q
E
L
G
T
Nematode Worm
Caenorhab. elegans
Q95YF3
430
48695
E396
R
H
T
L
R
R
I
E
Q
E
L
R
T
R
I
Sea Urchin
Strong. purpuratus
XP_001192557
538
61021
V500
D
D
R
V
P
M
Y
V
I
E
K
E
L
S
T
Poplar Tree
Populus trichocarpa
XP_002301349
499
57224
L465
H
L
G
L
A
V
N
L
I
T
Y
E
D
R
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M2E0
498
56756
L464
H
L
G
L
A
V
N
L
V
T
Y
E
D
R
F
Baker's Yeast
Sacchar. cerevisiae
P39517
506
57526
P468
H
P
Q
F
M
V
P
P
S
H
Q
Q
Q
Q
A
Red Bread Mold
Neurospora crassa
Q7S5D9
505
56636
R469
P
G
S
S
R
G
G
R
G
R
G
F
Q
G
Q
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
99.7
N.A.
97.7
98.1
N.A.
89.6
99.1
94.8
89.2
N.A.
65.4
67.2
62.9
59.4
Protein Similarity:
100
N.A.
N.A.
100
N.A.
98.3
98.5
N.A.
90.4
99.5
97.9
93.5
N.A.
78.4
78.4
74.7
73.9
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
60
66.6
6.6
46.6
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
86.6
86.6
13.3
66.6
Percent
Protein Identity:
60.9
N.A.
N.A.
62
57.7
57.6
Protein Similarity:
75.3
N.A.
N.A.
75.9
70.7
71.6
P-Site Identity:
6.6
N.A.
N.A.
0
13.3
6.6
P-Site Similarity:
20
N.A.
N.A.
20
33.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
57
69
0
0
7
0
0
0
0
0
0
0
13
0
0
% D
% Glu:
13
0
0
0
0
0
0
7
0
75
50
32
0
0
0
% E
% Phe:
0
0
0
69
0
0
0
0
0
0
0
7
0
0
13
% F
% Gly:
0
7
13
0
0
7
7
7
7
0
7
0
0
69
0
% G
% His:
19
7
0
0
0
0
13
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
7
0
75
0
0
0
0
0
7
% I
% Lys:
0
0
0
0
0
0
50
0
0
0
13
0
0
0
0
% K
% Leu:
0
13
0
19
0
63
0
13
0
0
7
0
69
0
0
% L
% Met:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
57
0
13
0
0
0
0
0
0
0
0
% N
% Pro:
7
7
0
0
7
0
7
7
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
0
0
0
7
0
13
57
13
7
7
% Q
% Arg:
7
0
69
0
13
7
0
19
0
7
0
7
0
19
0
% R
% Ser:
0
0
7
7
0
0
0
44
7
0
0
0
0
7
0
% S
% Thr:
0
0
7
0
0
0
0
0
0
13
0
0
7
0
69
% T
% Val:
0
0
0
7
0
19
0
7
7
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
0
0
13
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _