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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX6 All Species: 20
Human Site: S92 Identified Species: 29.33
UniProt: P26196 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P26196 NP_004388.2 483 54417 S92 I K T S D V T S T K G N E F E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536551 483 54384 S92 I K T S D V T S T K G N E F E
Cat Felis silvestris
Mouse Mus musculus P54823 483 54173 S92 I K T S D V T S T K G N E F E
Rat Rattus norvegicus NP_001102762 483 54226 S92 I K T S D V T S T K G N E F E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516184 444 50248 L92 E E S I P I A L S G R D I L A
Chicken Gallus gallus Q5ZKB9 483 54399 S92 I K T S D V T S T K G N E F E
Frog Xenopus laevis P54824 481 54055 T92 K T S D V T S T K G N E F E D
Zebra Danio Brachydanio rerio XP_684923 484 53892 A93 M K T S D V T A T K G N E F E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P23128 459 51927 S94 A A I P I A L S G K D V L A R
Honey Bee Apis mellifera XP_624586 443 50482 K92 I P I A L S G K D I L A R A K
Nematode Worm Caenorhab. elegans Q95YF3 430 48695 K88 Q D I L A R A K N G T G K T G
Sea Urchin Strong. purpuratus XP_001192557 538 61021 D145 I R T T D V T D T K G N E F E
Poplar Tree Populus trichocarpa XP_002301349 499 57224 A121 Y R T E D V T A T K G N D F E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M2E0 498 56756 A120 Y Q T A D V T A T K G N E F E
Baker's Yeast Sacchar. cerevisiae P39517 506 57526 I102 G K T A A F V I P T L E K V K
Red Bread Mold Neurospora crassa Q7S5D9 505 56636 I101 G K T A A F V I P A L N K I N
Conservation
Percent
Protein Identity: 100 N.A. N.A. 99.7 N.A. 97.7 98.1 N.A. 89.6 99.1 94.8 89.2 N.A. 65.4 67.2 62.9 59.4
Protein Similarity: 100 N.A. N.A. 100 N.A. 98.3 98.5 N.A. 90.4 99.5 97.9 93.5 N.A. 78.4 78.4 74.7 73.9
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 0 100 0 86.6 N.A. 13.3 6.6 0 80
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 33.3 100 26.6 100 N.A. 13.3 20 6.6 93.3
Percent
Protein Identity: 60.9 N.A. N.A. 62 57.7 57.6
Protein Similarity: 75.3 N.A. N.A. 75.9 70.7 71.6
P-Site Identity: 66.6 N.A. N.A. 73.3 13.3 20
P-Site Similarity: 86.6 N.A. N.A. 93.3 33.3 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 0 25 19 7 13 19 0 7 0 7 0 13 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 7 57 0 0 7 7 0 7 7 7 0 7 % D
% Glu: 7 7 0 7 0 0 0 0 0 0 0 13 50 7 57 % E
% Phe: 0 0 0 0 0 13 0 0 0 0 0 0 7 57 0 % F
% Gly: 13 0 0 0 0 0 7 0 7 19 57 7 0 0 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 44 0 19 7 7 7 0 13 0 7 0 0 7 7 0 % I
% Lys: 7 50 0 0 0 0 0 13 7 63 0 0 19 0 13 % K
% Leu: 0 0 0 7 7 0 7 7 0 0 19 0 7 7 0 % L
% Met: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 7 0 7 63 0 0 7 % N
% Pro: 0 7 0 7 7 0 0 0 13 0 0 0 0 0 0 % P
% Gln: 7 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 13 0 0 0 7 0 0 0 0 7 0 7 0 7 % R
% Ser: 0 0 13 38 0 7 7 38 7 0 0 0 0 0 0 % S
% Thr: 0 7 69 7 0 7 57 7 57 7 7 0 0 7 0 % T
% Val: 0 0 0 0 7 57 13 0 0 0 0 7 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _