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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX6
All Species:
38.18
Human Site:
T199
Identified Species:
56
UniProt:
P26196
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26196
NP_004388.2
483
54417
T199
G
G
A
K
V
M
A
T
T
G
G
T
N
L
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536551
483
54384
T199
G
G
A
K
V
M
A
T
T
G
G
T
N
L
R
Cat
Felis silvestris
Mouse
Mus musculus
P54823
483
54173
T199
G
G
A
K
V
M
A
T
T
G
G
T
N
L
R
Rat
Rattus norvegicus
NP_001102762
483
54226
T199
G
G
A
K
V
M
A
T
T
G
G
T
N
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516184
444
50248
K193
R
I
L
D
L
I
K
K
G
V
A
K
V
D
H
Chicken
Gallus gallus
Q5ZKB9
483
54399
T199
G
G
A
K
V
M
A
T
T
G
G
T
N
L
R
Frog
Xenopus laevis
P54824
481
54055
T198
G
G
A
K
V
M
A
T
T
G
G
T
N
L
R
Zebra Danio
Brachydanio rerio
XP_684923
484
53892
T200
G
G
V
K
V
M
A
T
T
G
G
T
N
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23128
459
51927
D192
G
R
I
L
D
L
M
D
K
K
V
A
D
M
S
Honey Bee
Apis mellifera
XP_624586
443
50482
D188
G
R
I
L
D
L
M
D
K
N
V
A
N
M
D
Nematode Worm
Caenorhab. elegans
Q95YF3
430
48695
M183
M
E
K
G
V
A
K
M
E
H
C
K
T
L
V
Sea Urchin
Strong. purpuratus
XP_001192557
538
61021
T251
T
G
H
N
V
M
V
T
T
G
G
T
S
L
R
Poplar Tree
Populus trichocarpa
XP_002301349
499
57224
T227
L
K
I
Q
V
M
A
T
T
G
G
T
S
L
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M2E0
498
56756
T226
L
N
I
Q
V
M
V
T
T
G
G
T
S
L
R
Baker's Yeast
Sacchar. cerevisiae
P39517
506
57526
T228
Q
S
L
L
F
S
A
T
F
P
L
T
V
K
E
Red Bread Mold
Neurospora crassa
Q7S5D9
505
56636
A226
R
Q
V
M
L
F
S
A
T
F
P
L
S
V
K
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
99.7
N.A.
97.7
98.1
N.A.
89.6
99.1
94.8
89.2
N.A.
65.4
67.2
62.9
59.4
Protein Similarity:
100
N.A.
N.A.
100
N.A.
98.3
98.5
N.A.
90.4
99.5
97.9
93.5
N.A.
78.4
78.4
74.7
73.9
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
0
100
100
93.3
N.A.
6.6
13.3
13.3
66.6
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
13.3
100
100
93.3
N.A.
26.6
26.6
13.3
73.3
Percent
Protein Identity:
60.9
N.A.
N.A.
62
57.7
57.6
Protein Similarity:
75.3
N.A.
N.A.
75.9
70.7
71.6
P-Site Identity:
60
N.A.
N.A.
60
20
6.6
P-Site Similarity:
80
N.A.
N.A.
73.3
20
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
38
0
0
7
57
7
0
0
7
13
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
0
0
0
7
13
0
0
13
0
0
0
0
7
7
7
% D
% Glu:
0
7
0
0
0
0
0
0
7
0
0
0
0
0
7
% E
% Phe:
0
0
0
0
7
7
0
0
7
7
0
0
0
0
0
% F
% Gly:
57
50
0
7
0
0
0
0
7
63
63
0
0
0
0
% G
% His:
0
0
7
0
0
0
0
0
0
7
0
0
0
0
7
% H
% Ile:
0
7
25
0
0
7
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
7
7
44
0
0
13
7
13
7
0
13
0
7
13
% K
% Leu:
13
0
13
19
13
13
0
0
0
0
7
7
0
69
0
% L
% Met:
7
0
0
7
0
63
13
7
0
0
0
0
0
13
0
% M
% Asn:
0
7
0
7
0
0
0
0
0
7
0
0
50
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
0
% P
% Gln:
7
7
0
13
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
13
13
0
0
0
0
0
0
0
0
0
0
0
0
57
% R
% Ser:
0
7
0
0
0
7
7
0
0
0
0
0
25
0
7
% S
% Thr:
7
0
0
0
0
0
0
69
69
0
0
69
7
0
0
% T
% Val:
0
0
13
0
69
0
13
0
0
7
13
0
13
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _