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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX6 All Species: 27.27
Human Site: T317 Identified Species: 40
UniProt: P26196 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P26196 NP_004388.2 483 54417 T317 T Q Y Y A Y V T E R Q K V H C
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536551 483 54384 T317 T Q Y Y A Y V T E R Q K V H C
Cat Felis silvestris
Mouse Mus musculus P54823 483 54173 T317 T Q Y Y A Y V T E R Q K V H C
Rat Rattus norvegicus NP_001102762 483 54226 T317 T Q Y Y A Y V T E R Q K V H C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516184 444 50248 I295 T L F S R L Q I N Q S I I F C
Chicken Gallus gallus Q5ZKB9 483 54399 T317 T Q Y Y A Y V T E R Q K V H C
Frog Xenopus laevis P54824 481 54055 T316 T Q Y Y A Y V T E R Q K V H C
Zebra Danio Brachydanio rerio XP_684923 484 53892 T318 T Q Y Y A Y V T E R Q K V H C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P23128 459 51927 Q294 N T L F S K L Q I N Q S I I F
Honey Bee Apis mellifera XP_624586 443 50482 Q290 N T L F S K L Q I T Q S I I F
Nematode Worm Caenorhab. elegans Q95YF3 430 48695 I285 L Q I N Q S I I F C N S T Q R
Sea Urchin Strong. purpuratus XP_001192557 538 61021 E369 T Q Y Y A F V E E K Q K V H C
Poplar Tree Populus trichocarpa XP_002301349 499 57224 E345 T Q Y Y A F V E E R Q K V H C
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M2E0 498 56756 E344 T Q Y Y A F V E E R Q K V H C
Baker's Yeast Sacchar. cerevisiae P39517 506 57526 Q331 K V F H E F R Q G K V R T L V
Red Bread Mold Neurospora crassa Q7S5D9 505 56636 N330 R V F H D F R N G V C R N L V
Conservation
Percent
Protein Identity: 100 N.A. N.A. 99.7 N.A. 97.7 98.1 N.A. 89.6 99.1 94.8 89.2 N.A. 65.4 67.2 62.9 59.4
Protein Similarity: 100 N.A. N.A. 100 N.A. 98.3 98.5 N.A. 90.4 99.5 97.9 93.5 N.A. 78.4 78.4 74.7 73.9
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 13.3 100 100 100 N.A. 6.6 6.6 6.6 80
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 33.3 100 100 100 N.A. 33.3 33.3 13.3 93.3
Percent
Protein Identity: 60.9 N.A. N.A. 62 57.7 57.6
Protein Similarity: 75.3 N.A. N.A. 75.9 70.7 71.6
P-Site Identity: 86.6 N.A. N.A. 86.6 0 0
P-Site Similarity: 93.3 N.A. N.A. 93.3 33.3 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 63 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 7 7 0 0 0 69 % C
% Asp: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 7 0 0 19 63 0 0 0 0 0 0 % E
% Phe: 0 0 19 13 0 32 0 0 7 0 0 0 0 7 13 % F
% Gly: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % G
% His: 0 0 0 13 0 0 0 0 0 0 0 0 0 63 0 % H
% Ile: 0 0 7 0 0 0 7 13 13 0 0 7 19 13 0 % I
% Lys: 7 0 0 0 0 13 0 0 0 13 0 63 0 0 0 % K
% Leu: 7 7 13 0 0 7 13 0 0 0 0 0 0 13 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 13 0 0 7 0 0 0 7 7 7 7 0 7 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 69 0 0 7 0 7 19 0 7 75 0 0 7 0 % Q
% Arg: 7 0 0 0 7 0 13 0 0 57 0 13 0 0 7 % R
% Ser: 0 0 0 7 13 7 0 0 0 0 7 19 0 0 0 % S
% Thr: 69 13 0 0 0 0 0 44 0 7 0 0 13 0 0 % T
% Val: 0 13 0 0 0 0 63 0 0 7 7 0 63 0 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 63 63 0 44 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _