KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX6
All Species:
31.52
Human Site:
Y150
Identified Species:
46.22
UniProt:
P26196
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26196
NP_004388.2
483
54417
Y150
G
T
G
K
S
G
A
Y
L
I
P
L
L
E
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536551
483
54384
Y150
G
T
G
K
S
G
A
Y
L
I
P
L
L
E
R
Cat
Felis silvestris
Mouse
Mus musculus
P54823
483
54173
Y150
G
T
G
K
S
G
A
Y
L
I
P
L
L
E
R
Rat
Rattus norvegicus
NP_001102762
483
54226
Y150
G
T
G
K
S
G
A
Y
L
I
P
L
L
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516184
444
50248
K150
Q
I
C
I
Q
V
S
K
H
M
G
G
A
K
V
Chicken
Gallus gallus
Q5ZKB9
483
54399
Y150
G
T
G
K
S
G
A
Y
L
I
P
L
L
E
R
Frog
Xenopus laevis
P54824
481
54055
Y149
G
T
G
K
S
G
A
Y
L
I
P
L
L
E
R
Zebra Danio
Brachydanio rerio
XP_684923
484
53892
Y151
G
T
G
K
S
G
A
Y
L
I
P
L
L
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23128
459
51927
K151
Q
I
C
I
E
L
A
K
H
L
D
I
R
V
M
Honey Bee
Apis mellifera
XP_624586
443
50482
K147
Q
I
C
I
E
L
A
K
H
M
E
I
K
V
M
Nematode Worm
Caenorhab. elegans
Q95YF3
430
48695
V142
S
K
H
I
Q
L
K
V
M
V
T
T
G
G
T
Sea Urchin
Strong. purpuratus
XP_001192557
538
61021
Y203
G
T
G
K
T
G
A
Y
T
I
P
V
L
E
K
Poplar Tree
Populus trichocarpa
XP_002301349
499
57224
F179
G
T
G
K
T
A
A
F
C
V
P
A
L
E
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M2E0
498
56756
F178
G
T
G
K
T
G
A
F
C
I
P
V
L
E
K
Baker's Yeast
Sacchar. cerevisiae
P39517
506
57526
K182
V
L
D
L
A
S
R
K
V
A
D
L
S
D
C
Red Bread Mold
Neurospora crassa
Q7S5D9
505
56636
Q181
I
L
D
L
A
G
K
Q
V
A
D
L
S
E
C
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
99.7
N.A.
97.7
98.1
N.A.
89.6
99.1
94.8
89.2
N.A.
65.4
67.2
62.9
59.4
Protein Similarity:
100
N.A.
N.A.
100
N.A.
98.3
98.5
N.A.
90.4
99.5
97.9
93.5
N.A.
78.4
78.4
74.7
73.9
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
0
100
100
100
N.A.
6.6
6.6
0
73.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
20
100
100
100
N.A.
20
20
13.3
93.3
Percent
Protein Identity:
60.9
N.A.
N.A.
62
57.7
57.6
Protein Similarity:
75.3
N.A.
N.A.
75.9
70.7
71.6
P-Site Identity:
53.3
N.A.
N.A.
66.6
6.6
20
P-Site Similarity:
80
N.A.
N.A.
93.3
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
7
75
0
0
13
0
7
7
0
0
% A
% Cys:
0
0
19
0
0
0
0
0
13
0
0
0
0
0
13
% C
% Asp:
0
0
13
0
0
0
0
0
0
0
19
0
0
7
0
% D
% Glu:
0
0
0
0
13
0
0
0
0
0
7
0
0
69
0
% E
% Phe:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% F
% Gly:
63
0
63
0
0
63
0
0
0
0
7
7
7
7
0
% G
% His:
0
0
7
0
0
0
0
0
19
0
0
0
0
0
0
% H
% Ile:
7
19
0
25
0
0
0
0
0
57
0
13
0
0
0
% I
% Lys:
0
7
0
63
0
0
13
25
0
0
0
0
7
7
19
% K
% Leu:
0
13
0
13
0
19
0
0
44
7
0
57
63
0
0
% L
% Met:
0
0
0
0
0
0
0
0
7
13
0
0
0
0
13
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
63
0
0
0
0
% P
% Gln:
19
0
0
0
13
0
0
7
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
7
0
0
0
0
0
7
0
44
% R
% Ser:
7
0
0
0
44
7
7
0
0
0
0
0
13
0
0
% S
% Thr:
0
63
0
0
19
0
0
0
7
0
7
7
0
0
7
% T
% Val:
7
0
0
0
0
7
0
7
13
13
0
13
0
13
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _