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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTNNA2
All Species:
27.58
Human Site:
T497
Identified Species:
46.67
UniProt:
P26232
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26232
NP_004380.2
953
105313
T497
E
K
Q
V
R
V
L
T
E
A
V
D
D
I
T
Chimpanzee
Pan troglodytes
XP_515576
953
105237
T497
E
K
Q
V
R
V
L
T
E
A
V
D
D
I
T
Rhesus Macaque
Macaca mulatta
XP_001112948
953
105294
T497
E
K
Q
V
R
V
L
T
E
A
V
D
D
I
T
Dog
Lupus familis
XP_540203
909
100744
K491
V
F
K
D
Q
W
E
K
Q
V
R
V
L
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q61301
953
105267
T497
E
K
Q
V
R
V
L
T
E
A
V
D
D
I
T
Rat
Rattus norvegicus
NP_001100068
953
105267
T497
E
K
Q
V
R
V
L
T
E
A
V
D
D
I
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516414
732
81211
A320
I
S
G
A
A
L
M
A
D
S
S
C
T
R
D
Chicken
Gallus gallus
P30997
906
100673
F486
A
Q
D
N
M
D
V
F
K
D
Q
W
E
K
Q
Frog
Xenopus laevis
Q6GLP0
966
107082
T509
E
K
Q
V
R
V
L
T
E
A
V
D
D
I
T
Zebra Danio
Brachydanio rerio
B7ZC77
865
95838
K451
V
F
K
D
Q
W
E
K
Q
V
R
I
L
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35220
917
102426
V496
T
Y
R
Q
A
W
E
V
Q
V
R
I
L
T
E
Honey Bee
Apis mellifera
XP_625229
909
101515
N489
V
F
R
Q
A
W
E
N
Q
V
R
V
L
T
E
Nematode Worm
Caenorhab. elegans
P90947
927
103976
T493
F
D
K
V
R
L
L
T
T
A
L
D
N
I
T
Sea Urchin
Strong. purpuratus
XP_784341
911
102424
T492
V
F
K
D
Q
W
E
T
Q
V
R
L
L
T
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
100
94.4
N.A.
99.9
99.9
N.A.
60.6
94.2
95.4
87
N.A.
61
63.9
35.9
63.9
Protein Similarity:
100
99.5
100
94.7
N.A.
100
100
N.A.
68
94.6
96.8
89
N.A.
77.2
78.5
57
79.6
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
0
0
100
0
N.A.
0
0
53.3
6.6
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
26.6
26.6
100
20
N.A.
13.3
13.3
80
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
22
0
0
8
0
50
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
8
8
22
0
8
0
0
8
8
0
50
43
0
8
% D
% Glu:
43
0
0
0
0
0
36
0
43
0
0
0
8
0
36
% E
% Phe:
8
29
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
15
0
50
0
% I
% Lys:
0
43
29
0
0
0
0
15
8
0
0
0
0
8
0
% K
% Leu:
0
0
0
0
0
15
50
0
0
0
8
8
36
0
0
% L
% Met:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
8
0
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
43
15
22
0
0
0
36
0
8
0
0
0
8
% Q
% Arg:
0
0
15
0
50
0
0
0
0
0
36
0
0
8
0
% R
% Ser:
0
8
0
0
0
0
0
0
0
8
8
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
58
8
0
0
0
8
36
50
% T
% Val:
29
0
0
50
0
43
8
8
0
36
43
15
0
0
0
% V
% Trp:
0
0
0
0
0
36
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _