KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DNMT1
All Species:
10.91
Human Site:
S953
Identified Species:
21.82
UniProt:
P26358
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26358
NP_001124295.1
1616
183165
S953
F
T
F
N
I
K
L
S
S
P
V
K
R
P
R
Chimpanzee
Pan troglodytes
XP_001163722
1671
188922
S1008
F
T
F
N
I
K
L
S
S
P
V
K
R
P
R
Rhesus Macaque
Macaca mulatta
XP_001104704
1455
164736
K854
R
P
N
E
T
D
I
K
I
R
V
N
K
F
Y
Dog
Lupus familis
XP_533919
1645
185708
S984
F
T
F
N
I
K
L
S
S
P
V
K
R
P
R
Cat
Felis silvestris
Mouse
Mus musculus
P13864
1620
183170
A957
F
T
F
N
I
K
V
A
S
P
V
K
R
P
K
Rat
Rattus norvegicus
Q9Z330
1622
182755
S958
T
F
N
I
K
M
A
S
P
M
K
R
S
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q92072
1537
172889
A864
F
S
F
S
M
K
P
A
S
P
A
K
R
P
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002661304
1500
169062
D846
S
H
R
K
D
D
V
D
E
D
L
Y
P
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
NP_001164522
1366
157059
T777
K
L
Y
R
P
E
N
T
H
K
S
S
T
L
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780273
1618
181959
F950
L
L
P
E
A
F
S
F
N
I
K
Q
K
V
V
Poplar Tree
Populus trichocarpa
XP_002305346
1529
172691
A886
H
S
C
N
L
K
I
A
E
E
D
K
D
I
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P34881
1534
172412
I906
V
S
K
T
G
F
F
I
N
G
I
E
Y
S
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.6
88.4
89.6
N.A.
78
76.5
N.A.
N.A.
72.4
N.A.
66.1
N.A.
N.A.
47.5
N.A.
54.5
Protein Similarity:
100
96.7
88.9
93.6
N.A.
87
85.6
N.A.
N.A.
81.5
N.A.
76.9
N.A.
N.A.
62.2
N.A.
69.9
P-Site Identity:
100
100
6.6
100
N.A.
80
13.3
N.A.
N.A.
53.3
N.A.
0
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
20
100
N.A.
100
20
N.A.
N.A.
86.6
N.A.
13.3
N.A.
N.A.
20
N.A.
20
Percent
Protein Identity:
26.4
N.A.
N.A.
26.9
N.A.
N.A.
Protein Similarity:
45.4
N.A.
N.A.
43.6
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
9
25
0
0
9
0
0
0
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
17
0
9
0
9
9
0
9
0
0
% D
% Glu:
0
0
0
17
0
9
0
0
17
9
0
9
0
9
0
% E
% Phe:
42
9
42
0
0
17
9
9
0
0
0
0
0
9
9
% F
% Gly:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% G
% His:
9
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
34
0
17
9
9
9
9
0
0
9
0
% I
% Lys:
9
0
9
9
9
50
0
9
0
9
17
50
17
9
17
% K
% Leu:
9
17
0
0
9
0
25
0
0
0
9
0
0
9
0
% L
% Met:
0
0
0
0
9
9
0
0
0
9
0
0
0
0
9
% M
% Asn:
0
0
17
42
0
0
9
0
17
0
0
9
0
0
0
% N
% Pro:
0
9
9
0
9
0
9
0
9
42
0
0
9
42
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Q
% Arg:
9
0
9
9
0
0
0
0
0
9
0
9
42
0
34
% R
% Ser:
9
25
0
9
0
0
9
34
42
0
9
9
9
9
0
% S
% Thr:
9
34
0
9
9
0
0
9
0
0
0
0
9
0
0
% T
% Val:
9
0
0
0
0
0
17
0
0
0
42
0
0
9
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
9
9
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _