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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAX6 All Species: 15.15
Human Site: S308 Identified Species: 33.33
UniProt: P26367 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P26367 NP_000271.1 422 46683 S308 Q P T T P V S S F T S G S M L
Chimpanzee Pan troglodytes Q2VL62 341 36320 L228 K V E E W S S L G R N N F P A
Rhesus Macaque Macaca mulatta Q2VL61 341 36390 L228 K V E E W S S L G R N N F P A
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P47239 503 54920 S358 G A R H S F S S Y S D S F M N
Rat Rattus norvegicus P63016 422 46736 S308 Q P T T P V S S F T S G S M L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P47237 216 24450 T103 Y Q P I P Q P T T P G S M L G
Frog Xenopus laevis P55864 422 46668 S308 Q P T T P V S S F T S G S M L
Zebra Danio Brachydanio rerio P26630 437 48407 T323 Q P I P Q P T T P V S F T S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O18381 857 89474 G684 P S P I P Q Q G D L T P S S L
Honey Bee Apis mellifera XP_394648 597 62909 Y482 I A T M P D T Y S S M S S S L
Nematode Worm Caenorhab. elegans NP_001024570 455 51043 R321 S P A S T P N R F P S N N S A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 32.2 32.7 N.A. N.A. 29.6 99.7 N.A. N.A. 51.1 96.4 92.4 N.A. 35.9 45.5 50.1 N.A.
Protein Similarity: 100 44.3 44.7 N.A. N.A. 42.7 99.7 N.A. N.A. 51.1 98.3 93.5 N.A. 41.1 52.5 62.4 N.A.
P-Site Identity: 100 6.6 6.6 N.A. N.A. 20 100 N.A. N.A. 6.6 100 20 N.A. 20 26.6 20 N.A.
P-Site Similarity: 100 20 20 N.A. N.A. 33.3 100 N.A. N.A. 20 100 40 N.A. 26.6 40 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 10 0 0 0 0 0 0 0 0 0 0 0 28 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 0 10 0 10 0 0 0 0 % D
% Glu: 0 0 19 19 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 10 0 0 37 0 0 10 28 0 0 % F
% Gly: 10 0 0 0 0 0 0 10 19 0 10 28 0 0 19 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 10 19 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 19 0 10 0 0 0 10 46 % L
% Met: 0 0 0 10 0 0 0 0 0 0 10 0 10 37 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 19 28 10 0 10 % N
% Pro: 10 46 19 10 55 19 10 0 10 19 0 10 0 19 0 % P
% Gln: 37 10 0 0 10 19 10 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 10 0 0 0 0 10 0 19 0 0 0 0 0 % R
% Ser: 10 10 0 10 10 19 55 37 10 19 46 28 46 37 0 % S
% Thr: 0 0 37 28 10 0 19 19 10 28 10 0 10 0 0 % T
% Val: 0 19 0 0 0 28 0 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 19 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 10 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _