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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
U2AF2
All Species:
6.67
Human Site:
S28
Identified Species:
13.33
UniProt:
P26368
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26368
NP_001012496.1
475
53501
S28
E
N
R
H
R
K
R
S
H
S
R
S
R
S
R
Chimpanzee
Pan troglodytes
XP_530073
713
78555
R145
P
S
R
S
G
G
G
R
S
R
S
S
L
I
G
Rhesus Macaque
Macaca mulatta
XP_001091568
467
51268
C24
A
R
G
T
R
R
E
C
A
R
D
D
P
G
V
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P26369
475
53499
S28
E
N
R
H
R
K
R
S
H
S
R
S
R
S
R
Rat
Rattus norvegicus
Q63285
419
46487
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080595
456
51328
K26
D
K
E
N
R
H
R
K
R
S
R
S
R
S
K
Zebra Danio
Brachydanio rerio
NP_991252
475
53612
H31
E
R
D
K
E
N
R
H
R
R
R
S
P
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24562
416
46636
Honey Bee
Apis mellifera
XP_623055
432
48801
D17
D
R
Q
D
R
E
K
D
R
D
R
D
R
D
R
Nematode Worm
Caenorhab. elegans
P90978
496
55412
R63
N
D
R
K
K
R
K
R
S
R
S
R
D
R
D
Sea Urchin
Strong. purpuratus
XP_001189425
444
50005
S20
E
R
D
R
R
S
R
S
K
D
N
K
R
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L716
589
66297
D134
H
R
R
S
R
D
R
D
R
R
R
S
R
D
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.4
87.5
N.A.
N.A.
99.7
20
N.A.
N.A.
N.A.
92
86.3
N.A.
66.7
66.7
51.4
62.9
Protein Similarity:
100
57.2
89.2
N.A.
N.A.
99.7
37.6
N.A.
N.A.
N.A.
94.7
92.2
N.A.
77
77.8
62.5
75.5
P-Site Identity:
100
13.3
6.6
N.A.
N.A.
100
0
N.A.
N.A.
N.A.
46.6
40
N.A.
0
26.6
6.6
46.6
P-Site Similarity:
100
20
13.3
N.A.
N.A.
100
0
N.A.
N.A.
N.A.
66.6
40
N.A.
0
53.3
33.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
17
9
17
9
0
9
0
17
0
17
9
17
9
17
9
% D
% Glu:
34
0
9
0
9
9
9
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
9
9
9
0
0
0
0
0
0
9
9
% G
% His:
9
0
0
17
0
9
0
9
17
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
0
9
0
17
9
17
17
9
9
0
0
9
0
0
9
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
17
0
9
0
9
0
0
0
0
9
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
42
42
9
59
17
50
17
34
42
50
9
50
9
50
% R
% Ser:
0
9
0
17
0
9
0
25
17
25
17
50
0
42
0
% S
% Thr:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _