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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
U2AF2
All Species:
14.85
Human Site:
T350
Identified Species:
29.7
UniProt:
P26368
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26368
NP_001012496.1
475
53501
T350
T
L
V
S
P
P
S
T
I
N
Q
T
P
V
T
Chimpanzee
Pan troglodytes
XP_530073
713
78555
T588
A
K
N
A
T
L
S
T
I
N
Q
T
P
V
T
Rhesus Macaque
Macaca mulatta
XP_001091568
467
51268
T342
A
K
N
A
T
L
S
T
I
N
Q
T
P
V
T
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P26369
475
53499
T350
T
L
V
S
L
P
S
T
I
N
Q
T
P
V
T
Rat
Rattus norvegicus
Q63285
419
46487
F308
S
P
F
F
S
I
P
F
A
P
H
I
E
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080595
456
51328
T331
A
K
N
A
T
L
S
T
I
N
Q
T
P
V
T
Zebra Danio
Brachydanio rerio
NP_991252
475
53612
T353
T
M
T
S
I
N
E
T
P
V
T
L
Q
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24562
416
46636
P305
Q
S
V
M
L
Q
V
P
G
L
S
N
V
V
T
Honey Bee
Apis mellifera
XP_623055
432
48801
V320
Q
A
P
V
Q
I
Q
V
P
G
L
S
M
V
G
Nematode Worm
Caenorhab. elegans
P90978
496
55412
N376
N
Q
Q
R
H
N
T
N
L
P
N
S
A
S
A
Sea Urchin
Strong. purpuratus
XP_001189425
444
50005
M322
S
V
G
A
K
N
A
M
N
Q
G
Q
Q
V
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L716
589
66297
K459
I
Q
G
A
I
Q
P
K
P
E
Q
E
E
V
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.4
87.5
N.A.
N.A.
99.7
20
N.A.
N.A.
N.A.
92
86.3
N.A.
66.7
66.7
51.4
62.9
Protein Similarity:
100
57.2
89.2
N.A.
N.A.
99.7
37.6
N.A.
N.A.
N.A.
94.7
92.2
N.A.
77
77.8
62.5
75.5
P-Site Identity:
100
60
60
N.A.
N.A.
93.3
0
N.A.
N.A.
N.A.
60
26.6
N.A.
20
6.6
0
6.6
P-Site Similarity:
100
66.6
66.6
N.A.
N.A.
93.3
6.6
N.A.
N.A.
N.A.
66.6
33.3
N.A.
20
13.3
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
9
0
42
0
0
9
0
9
0
0
0
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% D
% Glu:
0
0
0
0
0
0
9
0
0
9
0
9
17
0
0
% E
% Phe:
0
0
9
9
0
0
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
17
0
0
0
0
0
9
9
9
0
0
0
9
% G
% His:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
9
0
0
0
17
17
0
0
42
0
0
9
0
0
0
% I
% Lys:
0
25
0
0
9
0
0
9
0
0
0
0
0
0
0
% K
% Leu:
0
17
0
0
17
25
0
0
9
9
9
9
0
0
17
% L
% Met:
0
9
0
9
0
0
0
9
0
0
0
0
9
0
0
% M
% Asn:
9
0
25
0
0
25
0
9
9
42
9
9
0
0
0
% N
% Pro:
0
9
9
0
9
17
17
9
25
17
0
0
42
0
9
% P
% Gln:
17
17
9
0
9
17
9
0
0
9
50
9
17
0
9
% Q
% Arg:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
17
9
0
25
9
0
42
0
0
0
9
17
0
9
0
% S
% Thr:
25
0
9
0
25
0
9
50
0
0
9
42
0
0
50
% T
% Val:
0
9
25
9
0
0
9
9
0
9
0
0
9
84
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _