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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
U2AF2
All Species:
33.94
Human Site:
T450
Identified Species:
67.88
UniProt:
P26368
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26368
NP_001012496.1
475
53501
T450
Q
K
A
M
Q
G
L
T
G
R
K
F
A
N
R
Chimpanzee
Pan troglodytes
XP_530073
713
78555
T688
Q
K
A
M
Q
G
L
T
G
R
K
F
A
N
R
Rhesus Macaque
Macaca mulatta
XP_001091568
467
51268
T442
Q
K
A
M
Q
G
L
T
G
R
K
F
A
N
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P26369
475
53499
T450
Q
K
A
M
Q
G
L
T
G
R
K
F
A
N
R
Rat
Rattus norvegicus
Q63285
419
46487
D395
L
L
T
G
R
M
F
D
G
K
F
V
V
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080595
456
51328
T431
Q
K
A
M
Q
G
L
T
G
R
K
F
A
N
R
Zebra Danio
Brachydanio rerio
NP_991252
475
53612
T450
Q
K
A
M
Q
G
L
T
G
R
K
F
A
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24562
416
46636
T392
Q
K
A
Q
Q
A
L
T
G
R
K
F
S
D
R
Honey Bee
Apis mellifera
XP_623055
432
48801
T408
Q
K
A
Q
Q
T
L
T
G
R
K
F
N
N
R
Nematode Worm
Caenorhab. elegans
P90978
496
55412
T472
Q
R
A
Q
A
A
L
T
G
R
K
F
A
N
R
Sea Urchin
Strong. purpuratus
XP_001189425
444
50005
A420
Q
A
A
Q
R
A
L
A
G
R
K
F
A
N
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L716
589
66297
N563
S
K
A
R
S
G
M
N
G
R
K
F
G
G
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.4
87.5
N.A.
N.A.
99.7
20
N.A.
N.A.
N.A.
92
86.3
N.A.
66.7
66.7
51.4
62.9
Protein Similarity:
100
57.2
89.2
N.A.
N.A.
99.7
37.6
N.A.
N.A.
N.A.
94.7
92.2
N.A.
77
77.8
62.5
75.5
P-Site Identity:
100
100
100
N.A.
N.A.
100
6.6
N.A.
N.A.
N.A.
100
100
N.A.
73.3
80
73.3
66.6
P-Site Similarity:
100
100
100
N.A.
N.A.
100
20
N.A.
N.A.
N.A.
100
100
N.A.
86.6
80
80
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
92
0
9
25
0
9
0
0
0
0
67
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
0
0
0
9
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
9
92
0
0
0
% F
% Gly:
0
0
0
9
0
59
0
0
100
0
0
0
9
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
75
0
0
0
0
0
0
0
9
92
0
0
0
0
% K
% Leu:
9
9
0
0
0
0
84
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
50
0
9
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
0
0
0
9
75
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
84
0
0
34
67
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
9
17
0
0
0
0
92
0
0
0
0
84
% R
% Ser:
9
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% S
% Thr:
0
0
9
0
0
9
0
75
0
0
0
0
0
0
9
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _