KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHML
All Species:
9.39
Human Site:
S349
Identified Species:
18.79
UniProt:
P26374
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26374
NP_001812.2
656
74071
S349
S
I
A
M
T
S
E
S
S
C
T
T
I
D
G
Chimpanzee
Pan troglodytes
XP_514301
656
74000
S349
S
I
A
M
T
S
E
S
S
C
T
T
I
D
G
Rhesus Macaque
Macaca mulatta
XP_001083432
653
73511
T347
S
I
A
M
T
S
E
T
A
S
S
T
I
D
G
Dog
Lupus familis
XP_537217
651
73192
T347
M
T
E
S
S
C
T
T
I
D
G
L
K
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZD5
621
69991
L339
P
N
L
Q
H
F
I
L
H
S
I
A
M
T
S
Rat
Rattus norvegicus
P37727
650
72462
C347
M
T
S
E
T
T
S
C
T
V
D
G
L
K
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026290
656
73072
N346
M
V
S
E
K
D
C
N
T
L
E
G
L
Q
A
Frog
Xenopus laevis
NP_001083662
643
71685
K345
A
K
T
V
E
G
L
K
A
M
Q
H
F
L
R
Zebra Danio
Brachydanio rerio
NP_982286
666
74108
F347
G
L
K
A
T
Q
H
F
L
R
C
L
G
R
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V8W3
511
56809
E229
G
P
S
T
S
F
E
E
G
M
Q
R
T
Q
R
Honey Bee
Apis mellifera
XP_001121784
523
59101
Q241
Y
G
S
G
E
L
P
Q
C
F
C
R
L
C
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39958
451
51188
L169
D
L
S
T
H
Q
G
L
D
L
D
K
N
T
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
71.1
84.9
N.A.
75.9
67.6
N.A.
N.A.
66.7
56.5
54.6
N.A.
30
35
N.A.
N.A.
Protein Similarity:
100
99.3
82.6
89.7
N.A.
83.8
78.5
N.A.
N.A.
78
74.3
71.6
N.A.
47.7
54.5
N.A.
N.A.
P-Site Identity:
100
100
73.3
0
N.A.
0
6.6
N.A.
N.A.
0
0
6.6
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
93.3
13.3
N.A.
6.6
33.3
N.A.
N.A.
33.3
20
13.3
N.A.
20
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
25
9
0
0
0
0
17
0
0
9
0
9
25
% A
% Cys:
0
0
0
0
0
9
9
9
9
17
17
0
0
9
0
% C
% Asp:
9
0
0
0
0
9
0
0
9
9
17
0
0
25
0
% D
% Glu:
0
0
9
17
17
0
34
9
0
0
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
17
0
9
0
9
0
0
9
0
0
% F
% Gly:
17
9
0
9
0
9
9
0
9
0
9
17
9
0
25
% G
% His:
0
0
0
0
17
0
9
0
9
0
0
9
0
0
0
% H
% Ile:
0
25
0
0
0
0
9
0
9
0
9
0
25
0
0
% I
% Lys:
0
9
9
0
9
0
0
9
0
0
0
9
9
9
0
% K
% Leu:
0
17
9
0
0
9
9
17
9
17
0
17
25
9
0
% L
% Met:
25
0
0
25
0
0
0
0
0
17
0
0
9
0
9
% M
% Asn:
0
9
0
0
0
0
0
9
0
0
0
0
9
0
0
% N
% Pro:
9
9
0
0
0
0
9
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
9
0
17
0
9
0
0
17
0
0
17
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
0
17
0
9
17
% R
% Ser:
25
0
42
9
17
25
9
17
17
17
9
0
0
0
9
% S
% Thr:
0
17
9
17
42
9
9
17
17
0
17
25
9
17
9
% T
% Val:
0
9
0
9
0
0
0
0
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _