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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHML
All Species:
21.52
Human Site:
S442
Identified Species:
43.03
UniProt:
P26374
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26374
NP_001812.2
656
74071
S442
I
V
E
D
S
Y
L
S
E
E
T
C
S
N
V
Chimpanzee
Pan troglodytes
XP_514301
656
74000
S442
I
V
E
D
S
Y
L
S
E
E
T
C
S
N
V
Rhesus Macaque
Macaca mulatta
XP_001083432
653
73511
S440
L
V
E
D
S
Y
F
S
E
N
M
C
S
R
V
Dog
Lupus familis
XP_537217
651
73192
S436
I
V
E
D
S
Y
L
S
E
E
T
C
S
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZD5
621
69991
F424
C
K
G
I
I
D
A
F
G
Q
R
I
S
A
N
Rat
Rattus norvegicus
P37727
650
72462
S437
I
I
E
D
S
Y
L
S
E
N
T
C
S
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026290
656
73072
S436
I
V
E
D
S
Y
L
S
E
S
V
C
E
N
V
Frog
Xenopus laevis
NP_001083662
643
71685
E430
V
E
D
S
Y
L
P
E
Q
I
C
A
N
V
S
Zebra Danio
Brachydanio rerio
NP_982286
666
74108
S432
I
R
E
E
Q
R
E
S
I
D
Y
R
Q
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V8W3
511
56809
P314
V
S
A
P
G
Y
T
P
V
S
K
G
I
E
L
Honey Bee
Apis mellifera
XP_001121784
523
59101
L326
G
E
K
E
N
L
T
L
L
Y
Y
P
P
E
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39958
451
51188
G254
A
R
L
S
A
I
Y
G
G
T
Y
M
L
D
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
71.1
84.9
N.A.
75.9
67.6
N.A.
N.A.
66.7
56.5
54.6
N.A.
30
35
N.A.
N.A.
Protein Similarity:
100
99.3
82.6
89.7
N.A.
83.8
78.5
N.A.
N.A.
78
74.3
71.6
N.A.
47.7
54.5
N.A.
N.A.
P-Site Identity:
100
100
66.6
100
N.A.
6.6
80
N.A.
N.A.
80
0
20
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
73.3
100
N.A.
13.3
86.6
N.A.
N.A.
80
26.6
33.3
N.A.
20
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
9
0
9
0
0
0
0
9
0
9
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
9
50
0
0
0
% C
% Asp:
0
0
9
50
0
9
0
0
0
9
0
0
0
9
0
% D
% Glu:
0
17
59
17
0
0
9
9
50
25
0
0
9
17
0
% E
% Phe:
0
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% F
% Gly:
9
0
9
0
9
0
0
9
17
0
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
50
9
0
9
9
9
0
0
9
9
0
9
9
9
0
% I
% Lys:
0
9
9
0
0
0
0
0
0
0
9
0
0
0
0
% K
% Leu:
9
0
9
0
0
17
42
9
9
0
0
0
9
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
17
0
0
9
34
9
% N
% Pro:
0
0
0
9
0
0
9
9
0
0
0
9
9
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
9
9
0
0
9
0
9
% Q
% Arg:
0
17
0
0
0
9
0
0
0
0
9
9
0
17
0
% R
% Ser:
0
9
0
17
50
0
0
59
0
17
0
0
50
0
17
% S
% Thr:
0
0
0
0
0
0
17
0
0
9
34
0
0
0
9
% T
% Val:
17
42
0
0
0
0
0
0
9
0
9
0
0
9
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
59
9
0
0
9
25
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _