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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHML
All Species:
13.64
Human Site:
S566
Identified Species:
27.27
UniProt:
P26374
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26374
NP_001812.2
656
74071
S566
S
S
G
I
S
R
S
S
Y
N
G
L
P
S
N
Chimpanzee
Pan troglodytes
XP_514301
656
74000
L566
S
S
G
I
S
R
S
L
Y
N
G
L
P
S
N
Rhesus Macaque
Macaca mulatta
XP_001083432
653
73511
C564
S
S
D
I
S
R
S
C
Y
K
D
L
P
S
N
Dog
Lupus familis
XP_537217
651
73192
S561
S
S
G
I
S
R
S
S
Y
N
G
L
P
S
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZD5
621
69991
R546
K
D
E
L
R
K
P
R
L
L
W
A
L
Y
F
Rat
Rattus norvegicus
P37727
650
72462
C561
S
S
D
I
S
R
D
C
Y
N
D
L
P
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026290
656
73072
S562
S
S
G
I
D
R
N
S
Y
S
G
L
P
S
N
Frog
Xenopus laevis
NP_001083662
643
71685
S553
S
S
G
V
P
R
Q
S
Y
V
G
L
P
S
N
Zebra Danio
Brachydanio rerio
NP_982286
666
74108
C554
T
S
A
M
D
S
S
C
Y
S
L
P
S
N
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V8W3
511
56809
D436
A
E
H
I
Y
Y
T
D
P
P
T
Y
E
L
D
Honey Bee
Apis mellifera
XP_001121784
523
59101
S448
K
L
N
D
S
T
P
S
N
L
H
L
C
S
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39958
451
51188
E376
E
T
D
K
P
H
I
E
L
E
P
A
F
K
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
71.1
84.9
N.A.
75.9
67.6
N.A.
N.A.
66.7
56.5
54.6
N.A.
30
35
N.A.
N.A.
Protein Similarity:
100
99.3
82.6
89.7
N.A.
83.8
78.5
N.A.
N.A.
78
74.3
71.6
N.A.
47.7
54.5
N.A.
N.A.
P-Site Identity:
100
93.3
73.3
100
N.A.
0
73.3
N.A.
N.A.
80
73.3
20
N.A.
6.6
26.6
N.A.
N.A.
P-Site Similarity:
100
93.3
73.3
100
N.A.
13.3
73.3
N.A.
N.A.
93.3
80
46.6
N.A.
26.6
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
0
0
0
0
0
0
17
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
25
0
0
0
0
9
0
0
% C
% Asp:
0
9
25
9
17
0
9
9
0
0
17
0
0
0
9
% D
% Glu:
9
9
9
0
0
0
0
9
0
9
0
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% F
% Gly:
0
0
42
0
0
0
0
0
0
0
42
0
0
0
9
% G
% His:
0
0
9
0
0
9
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
59
0
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
17
0
0
9
0
9
0
0
0
9
0
0
0
9
0
% K
% Leu:
0
9
0
9
0
0
0
9
17
17
9
67
9
9
9
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
9
0
9
34
0
0
0
9
59
% N
% Pro:
0
0
0
0
17
0
17
0
9
9
9
9
59
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
9
59
0
9
0
0
0
0
0
0
0
% R
% Ser:
59
67
0
0
50
9
42
42
0
17
0
0
9
67
0
% S
% Thr:
9
9
0
0
0
9
9
0
0
0
9
0
0
0
0
% T
% Val:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
9
9
0
0
67
0
0
9
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _