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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHML
All Species:
16.97
Human Site:
T603
Identified Species:
33.94
UniProt:
P26374
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26374
NP_001812.2
656
74071
T603
L
F
Q
E
I
F
P
T
E
E
F
C
P
P
P
Chimpanzee
Pan troglodytes
XP_514301
656
74000
T603
L
F
Q
E
I
F
P
T
E
E
F
C
P
P
P
Rhesus Macaque
Macaca mulatta
XP_001083432
653
73511
S601
L
F
Q
E
I
C
P
S
E
D
F
C
P
P
P
Dog
Lupus familis
XP_537217
651
73192
N598
L
F
Q
E
I
F
P
N
E
D
F
C
P
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZD5
621
69991
W581
Y
I
C
S
G
P
D
W
G
L
G
S
E
H
A
Rat
Rattus norvegicus
P37727
650
72462
N598
L
F
Q
Q
I
C
P
N
E
D
F
C
P
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026290
656
73072
T599
I
F
Q
E
M
F
P
T
E
E
F
C
P
A
P
Frog
Xenopus laevis
NP_001083662
643
71685
S590
I
F
H
D
L
Y
P
S
E
E
F
C
P
P
A
Zebra Danio
Brachydanio rerio
NP_982286
666
74108
D590
V
F
H
C
L
L
P
D
E
E
F
C
P
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V8W3
511
56809
P471
F
L
P
R
A
P
D
P
E
E
I
V
V
D
G
Honey Bee
Apis mellifera
XP_001121784
523
59101
L483
M
Y
P
D
Q
D
F
L
P
R
A
P
D
P
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39958
451
51188
L411
G
S
K
D
N
I
Y
L
S
R
S
Y
D
A
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
71.1
84.9
N.A.
75.9
67.6
N.A.
N.A.
66.7
56.5
54.6
N.A.
30
35
N.A.
N.A.
Protein Similarity:
100
99.3
82.6
89.7
N.A.
83.8
78.5
N.A.
N.A.
78
74.3
71.6
N.A.
47.7
54.5
N.A.
N.A.
P-Site Identity:
100
100
80
86.6
N.A.
0
66.6
N.A.
N.A.
80
53.3
53.3
N.A.
13.3
6.6
N.A.
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
0
80
N.A.
N.A.
93.3
86.6
66.6
N.A.
13.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
0
0
9
0
0
25
25
% A
% Cys:
0
0
9
9
0
17
0
0
0
0
0
67
0
0
0
% C
% Asp:
0
0
0
25
0
9
17
9
0
25
0
0
17
9
0
% D
% Glu:
0
0
0
42
0
0
0
0
75
50
0
0
9
0
9
% E
% Phe:
9
67
0
0
0
34
9
0
0
0
67
0
0
0
0
% F
% Gly:
9
0
0
0
9
0
0
0
9
0
9
0
0
0
9
% G
% His:
0
0
17
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
17
9
0
0
42
9
0
0
0
0
9
0
0
0
0
% I
% Lys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
42
9
0
0
17
9
0
17
0
9
0
0
0
0
0
% L
% Met:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
17
0
0
0
0
0
0
0
% N
% Pro:
0
0
17
0
0
17
67
9
9
0
0
9
67
59
50
% P
% Gln:
0
0
50
9
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
0
0
0
0
0
17
0
0
0
0
0
% R
% Ser:
0
9
0
9
0
0
0
17
9
0
9
9
0
0
9
% S
% Thr:
0
0
0
0
0
0
0
25
0
0
0
0
0
0
0
% T
% Val:
9
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
9
9
0
0
0
9
9
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _