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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHML
All Species:
4.55
Human Site:
T88
Identified Species:
9.09
UniProt:
P26374
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26374
NP_001812.2
656
74071
T88
H
E
T
E
E
A
I
T
L
R
K
K
D
E
T
Chimpanzee
Pan troglodytes
XP_514301
656
74000
T88
H
E
T
E
E
A
I
T
L
R
K
K
D
E
T
Rhesus Macaque
Macaca mulatta
XP_001083432
653
73511
L88
E
N
E
E
A
I
A
L
S
R
K
D
K
T
I
Dog
Lupus familis
XP_537217
651
73192
A88
H
E
T
E
E
A
I
A
L
R
K
K
D
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZD5
621
69991
E82
T
W
Q
D
L
I
H
E
T
E
E
A
I
S
L
Rat
Rattus norvegicus
P37727
650
72462
L88
E
N
E
E
A
I
P
L
S
S
K
D
K
T
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026290
656
73072
L88
E
N
E
E
V
I
S
L
N
K
K
D
K
T
I
Frog
Xenopus laevis
NP_001083662
643
71685
N88
N
E
E
I
I
P
F
N
K
R
N
Q
T
I
Q
Zebra Danio
Brachydanio rerio
NP_982286
666
74108
V89
I
E
D
G
E
E
A
V
P
L
N
S
V
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V8W3
511
56809
Honey Bee
Apis mellifera
XP_001121784
523
59101
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39958
451
51188
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
71.1
84.9
N.A.
75.9
67.6
N.A.
N.A.
66.7
56.5
54.6
N.A.
30
35
N.A.
N.A.
Protein Similarity:
100
99.3
82.6
89.7
N.A.
83.8
78.5
N.A.
N.A.
78
74.3
71.6
N.A.
47.7
54.5
N.A.
N.A.
P-Site Identity:
100
100
20
93.3
N.A.
0
13.3
N.A.
N.A.
13.3
13.3
13.3
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
100
20
93.3
N.A.
13.3
13.3
N.A.
N.A.
20
26.6
26.6
N.A.
0
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
17
25
17
9
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
9
0
0
0
0
0
0
0
25
25
9
0
% D
% Glu:
25
42
34
50
34
9
0
9
0
9
9
0
0
25
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
25
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
9
9
34
25
0
0
0
0
0
9
9
25
% I
% Lys:
0
0
0
0
0
0
0
0
9
9
50
25
25
0
0
% K
% Leu:
0
0
0
0
9
0
0
25
25
9
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
25
0
0
0
0
0
9
9
0
17
0
0
0
0
% N
% Pro:
0
0
0
0
0
9
9
0
9
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
0
9
0
0
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
42
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
9
0
17
9
0
9
0
9
9
% S
% Thr:
9
0
25
0
0
0
0
17
9
0
0
0
9
25
25
% T
% Val:
0
0
0
0
9
0
0
9
0
0
0
0
9
0
0
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _