KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHML
All Species:
8.79
Human Site:
Y219
Identified Species:
17.58
UniProt:
P26374
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26374
NP_001812.2
656
74071
Y219
P
I
R
N
R
I
T
Y
S
Q
I
V
K
E
G
Chimpanzee
Pan troglodytes
XP_514301
656
74000
Y219
P
I
R
N
R
I
T
Y
S
Q
I
V
K
E
G
Rhesus Macaque
Macaca mulatta
XP_001083432
653
73511
Y217
P
K
K
N
R
I
T
Y
S
Q
I
I
K
E
G
Dog
Lupus familis
XP_537217
651
73192
Q216
R
N
R
I
T
Y
S
Q
I
V
K
E
G
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZD5
621
69991
Q210
V
V
Q
D
S
I
E
Q
P
K
R
N
R
I
T
Rat
Rattus norvegicus
P37727
650
72462
I218
R
I
T
Y
S
Q
I
I
K
E
G
R
R
F
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026290
656
73072
V217
K
I
T
Y
S
Q
I
V
R
E
G
R
R
F
N
Frog
Xenopus laevis
NP_001083662
643
71685
R216
Q
I
V
K
E
G
R
R
F
N
I
D
L
V
S
Zebra Danio
Brachydanio rerio
NP_982286
666
74108
L218
G
R
R
F
N
I
D
L
V
S
K
L
M
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V8W3
511
56809
R100
D
S
V
L
A
K
S
R
R
F
S
L
D
L
C
Honey Bee
Apis mellifera
XP_001121784
523
59101
I112
K
Q
W
S
I
D
R
I
R
K
E
Y
R
K
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39958
451
51188
K40
K
K
V
L
H
I
D
K
Q
D
H
Y
G
G
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
71.1
84.9
N.A.
75.9
67.6
N.A.
N.A.
66.7
56.5
54.6
N.A.
30
35
N.A.
N.A.
Protein Similarity:
100
99.3
82.6
89.7
N.A.
83.8
78.5
N.A.
N.A.
78
74.3
71.6
N.A.
47.7
54.5
N.A.
N.A.
P-Site Identity:
100
100
80
6.6
N.A.
6.6
6.6
N.A.
N.A.
6.6
13.3
13.3
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
100
93.3
13.3
N.A.
40
20
N.A.
N.A.
20
13.3
20
N.A.
13.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
9
0
0
9
0
9
17
0
0
9
0
9
9
0
0
% D
% Glu:
0
0
0
0
9
0
9
0
0
17
9
9
0
25
9
% E
% Phe:
0
0
0
9
0
0
0
0
9
9
0
0
0
17
9
% F
% Gly:
9
0
0
0
0
9
0
0
0
0
17
0
17
9
25
% G
% His:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
42
0
9
9
50
17
17
9
0
34
9
0
9
0
% I
% Lys:
25
17
9
9
0
9
0
9
9
17
17
0
25
9
0
% K
% Leu:
0
0
0
17
0
0
0
9
0
0
0
17
9
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
9
0
25
9
0
0
0
0
9
0
9
0
0
17
% N
% Pro:
25
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
9
9
9
0
0
17
0
17
9
25
0
0
0
0
0
% Q
% Arg:
17
9
34
0
25
0
17
17
25
0
9
17
34
9
9
% R
% Ser:
0
9
0
9
25
0
17
0
25
9
9
0
0
0
17
% S
% Thr:
0
0
17
0
9
0
25
0
0
0
0
0
0
0
9
% T
% Val:
9
9
25
0
0
0
0
9
9
9
0
17
0
9
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
17
0
9
0
25
0
0
0
17
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _