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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHML
All Species:
10
Human Site:
Y314
Identified Species:
20
UniProt:
P26374
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26374
NP_001812.2
656
74071
Y314
Y
E
Q
H
P
D
E
Y
Q
A
F
R
Q
C
S
Chimpanzee
Pan troglodytes
XP_514301
656
74000
Y314
Y
E
Q
H
P
D
E
Y
Q
A
F
R
Q
C
S
Rhesus Macaque
Macaca mulatta
XP_001083432
653
73511
Y312
Y
E
K
Y
P
D
E
Y
K
G
Y
E
D
I
T
Dog
Lupus familis
XP_537217
651
73192
F312
H
P
D
Q
Y
Q
A
F
V
H
C
S
F
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZD5
621
69991
L304
M
K
F
L
T
F
C
L
D
Y
E
Q
H
S
D
Rat
Rattus norvegicus
P37727
650
72462
Y312
H
P
D
E
Y
R
A
Y
E
G
T
T
F
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026290
656
73072
Y311
H
P
D
E
Y
Q
D
Y
K
N
S
T
F
A
Q
Frog
Xenopus laevis
NP_001083662
643
71685
F310
Q
D
Y
E
A
S
T
F
L
E
F
L
K
S
K
Zebra Danio
Brachydanio rerio
NP_982286
666
74108
K312
K
P
F
S
E
F
L
K
N
K
K
L
T
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V8W3
511
56809
G194
E
D
S
L
E
F
R
G
R
T
F
L
E
Y
L
Honey Bee
Apis mellifera
XP_001121784
523
59101
S206
A
M
A
T
E
K
T
S
C
R
D
G
V
N
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39958
451
51188
A134
V
P
A
N
E
I
E
A
I
S
S
P
L
M
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
71.1
84.9
N.A.
75.9
67.6
N.A.
N.A.
66.7
56.5
54.6
N.A.
30
35
N.A.
N.A.
Protein Similarity:
100
99.3
82.6
89.7
N.A.
83.8
78.5
N.A.
N.A.
78
74.3
71.6
N.A.
47.7
54.5
N.A.
N.A.
P-Site Identity:
100
100
40
0
N.A.
0
6.6
N.A.
N.A.
6.6
6.6
0
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
73.3
13.3
N.A.
13.3
20
N.A.
N.A.
26.6
26.6
6.6
N.A.
26.6
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
17
0
9
0
17
9
0
17
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
9
0
9
0
9
0
0
17
0
% C
% Asp:
0
17
25
0
0
25
9
0
9
0
9
0
9
0
17
% D
% Glu:
9
25
0
25
34
0
34
0
9
9
9
9
9
9
9
% E
% Phe:
0
0
17
0
0
25
0
17
0
0
34
0
25
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
17
0
9
0
0
9
% G
% His:
25
0
0
17
0
0
0
0
0
9
0
0
9
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
9
0
0
0
0
9
0
% I
% Lys:
9
9
9
0
0
9
0
9
17
9
9
0
9
0
9
% K
% Leu:
0
0
0
17
0
0
9
9
9
0
0
25
9
0
9
% L
% Met:
9
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
9
0
0
0
0
9
9
0
0
0
9
9
% N
% Pro:
0
42
0
0
25
0
0
0
0
0
0
9
0
0
0
% P
% Gln:
9
0
17
9
0
17
0
0
17
0
0
9
17
0
9
% Q
% Arg:
0
0
0
0
0
9
9
0
9
9
0
17
0
0
9
% R
% Ser:
0
0
9
9
0
9
0
9
0
9
17
9
0
34
17
% S
% Thr:
0
0
0
9
9
0
17
0
0
9
9
17
9
0
9
% T
% Val:
9
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
25
0
9
9
25
0
0
42
0
9
9
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _