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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHML
All Species:
21.21
Human Site:
Y440
Identified Species:
42.42
UniProt:
P26374
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26374
NP_001812.2
656
74071
Y440
Y
F
I
V
E
D
S
Y
L
S
E
E
T
C
S
Chimpanzee
Pan troglodytes
XP_514301
656
74000
Y440
Y
F
I
V
E
D
S
Y
L
S
E
E
T
C
S
Rhesus Macaque
Macaca mulatta
XP_001083432
653
73511
Y438
H
F
L
V
E
D
S
Y
F
S
E
N
M
C
S
Dog
Lupus familis
XP_537217
651
73192
Y434
Y
F
I
V
E
D
S
Y
L
S
E
E
T
C
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZD5
621
69991
D422
G
R
C
K
G
I
I
D
A
F
G
Q
R
I
S
Rat
Rattus norvegicus
P37727
650
72462
Y435
H
F
I
I
E
D
S
Y
L
S
E
N
T
C
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026290
656
73072
Y434
Y
F
I
V
E
D
S
Y
L
S
E
S
V
C
E
Frog
Xenopus laevis
NP_001083662
643
71685
L428
L
V
V
E
D
S
Y
L
P
E
Q
I
C
A
N
Zebra Danio
Brachydanio rerio
NP_982286
666
74108
R430
S
Y
I
R
E
E
Q
R
E
S
I
D
Y
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V8W3
511
56809
Y312
N
V
V
S
A
P
G
Y
T
P
V
S
K
G
I
Honey Bee
Apis mellifera
XP_001121784
523
59101
L324
M
Q
G
E
K
E
N
L
T
L
L
Y
Y
P
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39958
451
51188
I252
G
F
A
R
L
S
A
I
Y
G
G
T
Y
M
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
71.1
84.9
N.A.
75.9
67.6
N.A.
N.A.
66.7
56.5
54.6
N.A.
30
35
N.A.
N.A.
Protein Similarity:
100
99.3
82.6
89.7
N.A.
83.8
78.5
N.A.
N.A.
78
74.3
71.6
N.A.
47.7
54.5
N.A.
N.A.
P-Site Identity:
100
100
66.6
100
N.A.
6.6
80
N.A.
N.A.
80
0
20
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
80
100
N.A.
13.3
93.3
N.A.
N.A.
80
26.6
40
N.A.
13.3
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
0
9
0
9
0
0
0
0
9
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
9
50
0
% C
% Asp:
0
0
0
0
9
50
0
9
0
0
0
9
0
0
0
% D
% Glu:
0
0
0
17
59
17
0
0
9
9
50
25
0
0
9
% E
% Phe:
0
59
0
0
0
0
0
0
9
9
0
0
0
0
0
% F
% Gly:
17
0
9
0
9
0
9
0
0
9
17
0
0
9
0
% G
% His:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
50
9
0
9
9
9
0
0
9
9
0
9
9
% I
% Lys:
0
0
0
9
9
0
0
0
0
0
0
0
9
0
0
% K
% Leu:
9
0
9
0
9
0
0
17
42
9
9
0
0
0
9
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% M
% Asn:
9
0
0
0
0
0
9
0
0
0
0
17
0
0
9
% N
% Pro:
0
0
0
0
0
9
0
0
9
9
0
0
0
9
9
% P
% Gln:
0
9
0
0
0
0
9
0
0
0
9
9
0
0
9
% Q
% Arg:
0
9
0
17
0
0
0
9
0
0
0
0
9
9
0
% R
% Ser:
9
0
0
9
0
17
50
0
0
59
0
17
0
0
50
% S
% Thr:
0
0
0
0
0
0
0
0
17
0
0
9
34
0
0
% T
% Val:
0
17
17
42
0
0
0
0
0
0
9
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
34
9
0
0
0
0
9
59
9
0
0
9
25
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _