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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HSD3B2 All Species: 13.94
Human Site: S247 Identified Species: 30.67
UniProt: P26439 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P26439 NP_000189.1 372 42052 S247 R D P K K A P S V R G Q F Y Y
Chimpanzee Pan troglodytes XP_001142491 372 42093 S247 R D P K K A P S V R G Q F Y Y
Rhesus Macaque Macaca mulatta P27365 373 41987 S248 R D P K K A P S V Q G Q F Y Y
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P24815 373 42044 S248 R D P K K S T S I Q G Q F Y Y
Rat Rattus norvegicus Q62878 373 41939 N248 R D P K K S Q N V Q G Q F Y Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511034 347 38904 R222 R D P E R A P R L G G Q F F F
Chicken Gallus gallus NP_990449 377 42863 H252 Q V P Q K A R H I R G Q F Y Y
Frog Xenopus laevis Q0IH73 386 43592 K241 E A L T S E K K Y I A A G Q P
Zebra Danio Brachydanio rerio A8DZE7 387 43577 Q241 D A L T E K Q Q C R A A G Q A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q67ZE1 564 61686 S249 L A S G G D V S T K A A G Q A
Baker's Yeast Sacchar. cerevisiae P53199 349 38688 V222 D W T Y A G N V A D A H V L A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 96.2 N.A. N.A. 70.7 73.1 N.A. 50.8 56.2 28.5 31.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 97.5 N.A. N.A. 83.9 83.9 N.A. 67.4 70 43.7 45.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 N.A. N.A. 73.3 73.3 N.A. 53.3 60 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 N.A. N.A. 93.3 93.3 N.A. 86.6 80 0 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.9 26.8 N.A.
Protein Similarity: N.A. N.A. N.A. 35.1 44.3 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 28 0 0 10 46 0 0 10 0 37 28 0 0 28 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 19 55 0 0 0 10 0 0 0 10 0 0 0 0 0 % D
% Glu: 10 0 0 10 10 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 64 10 10 % F
% Gly: 0 0 0 10 10 10 0 0 0 10 64 0 28 0 0 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 19 10 0 0 0 0 0 % I
% Lys: 0 0 0 46 55 10 10 10 0 10 0 0 0 0 0 % K
% Leu: 10 0 19 0 0 0 0 0 10 0 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 64 0 0 0 37 0 0 0 0 0 0 0 10 % P
% Gln: 10 0 0 10 0 0 19 10 0 28 0 64 0 28 0 % Q
% Arg: 55 0 0 0 10 0 10 10 0 37 0 0 0 0 0 % R
% Ser: 0 0 10 0 10 19 0 46 0 0 0 0 0 0 0 % S
% Thr: 0 0 10 19 0 0 10 0 10 0 0 0 0 0 0 % T
% Val: 0 10 0 0 0 0 10 10 37 0 0 0 10 0 0 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 10 0 0 0 0 55 55 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _