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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IVD
All Species:
28.18
Human Site:
Y274
Identified Species:
62
UniProt:
P26440
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26440
NP_002216.2
423
46319
Y274
G
H
E
N
K
G
V
Y
V
L
M
S
G
L
D
Chimpanzee
Pan troglodytes
A5A6I0
421
46589
K271
I
G
D
G
A
G
F
K
V
A
M
G
A
F
D
Rhesus Macaque
Macaca mulatta
XP_001096354
423
46154
Y274
G
H
E
N
K
G
V
Y
V
L
M
S
G
L
D
Dog
Lupus familis
XP_535433
423
46416
Y274
G
H
L
S
K
G
V
Y
V
L
M
S
G
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHI5
424
46307
Y275
S
Q
E
S
K
G
V
Y
V
L
M
S
G
L
D
Rat
Rattus norvegicus
P12007
424
46417
Y275
S
Q
E
S
K
G
V
Y
V
L
M
S
G
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420942
422
45827
Y273
G
K
L
S
K
G
V
Y
V
L
M
S
G
L
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_958899
418
45766
Y269
G
P
L
N
K
G
V
Y
V
L
M
S
G
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSA3
419
45853
K267
I
G
E
G
A
G
F
K
I
A
M
G
T
F
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22347
417
44800
K261
G
A
P
G
A
G
F
K
V
A
M
E
A
F
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SWG0
409
44755
Y261
D
K
E
G
K
G
V
Y
V
L
M
S
G
L
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.1
97.1
91.2
N.A.
89.1
89.8
N.A.
N.A.
84.1
N.A.
74.6
N.A.
32.3
N.A.
34.9
N.A.
Protein Similarity:
100
52
98.5
94.8
N.A.
95.2
95.2
N.A.
N.A.
90.7
N.A.
87.4
N.A.
52.7
N.A.
53.1
N.A.
P-Site Identity:
100
26.6
100
86.6
N.A.
80
80
N.A.
N.A.
80
N.A.
86.6
N.A.
26.6
N.A.
33.3
N.A.
P-Site Similarity:
100
33.3
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
86.6
N.A.
86.6
N.A.
33.3
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
61.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
73.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
80
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
28
0
0
0
0
28
0
0
19
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
100
% D
% Glu:
0
0
55
0
0
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
28
0
0
0
0
0
0
28
0
% F
% Gly:
55
19
0
37
0
100
0
0
0
0
0
19
73
0
0
% G
% His:
0
28
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
19
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
19
0
0
73
0
0
28
0
0
0
0
0
0
0
% K
% Leu:
0
0
28
0
0
0
0
0
0
73
0
0
0
73
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% M
% Asn:
0
0
0
28
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
19
0
0
37
0
0
0
0
0
0
0
73
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
73
0
91
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
73
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _