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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
S100A4
All Species:
8.18
Human Site:
S60
Identified Species:
20
UniProt:
P26447
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26447
NP_002952.1
101
11729
S60
A
A
F
Q
K
L
M
S
N
L
D
S
N
R
D
Chimpanzee
Pan troglodytes
XP_513816
98
11125
G61
E
G
L
K
K
L
M
G
N
L
D
E
N
S
D
Rhesus Macaque
Macaca mulatta
XP_001110911
98
11116
G61
E
G
L
K
K
L
M
G
N
L
D
E
N
S
D
Dog
Lupus familis
XP_855158
97
10951
G60
E
G
L
K
K
L
M
G
N
L
D
E
N
S
D
Cat
Felis silvestris
Mouse
Mus musculus
P07091
101
11703
S60
A
A
F
Q
K
V
M
S
N
L
D
S
N
R
D
Rat
Rattus norvegicus
P05942
101
11758
N60
A
A
F
Q
K
L
M
N
N
L
D
S
N
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513231
101
11530
S60
A
G
L
Q
K
L
M
S
T
L
D
N
N
Q
D
Chicken
Gallus gallus
Q98953
92
10257
L60
I
A
G
L
M
E
D
L
D
R
N
K
D
Q
E
Frog
Xenopus laevis
P27004
96
11311
K59
M
T
V
D
K
I
M
K
D
L
D
D
C
R
K
Zebra Danio
Brachydanio rerio
NP_997926
95
10388
K61
A
A
L
D
K
I
F
K
D
L
D
A
N
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.3
61.3
61.3
N.A.
93
91
N.A.
74.2
47.5
32.6
53.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
78.2
78.2
78.2
N.A.
98
97
N.A.
88.1
66.3
58.4
68.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
53.3
53.3
53.3
N.A.
93.3
93.3
N.A.
66.6
6.6
33.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
60
60
60
N.A.
100
100
N.A.
80
40
46.6
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
50
0
0
0
0
0
0
0
0
0
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
20
0
0
10
0
30
0
90
10
10
0
80
% D
% Glu:
30
0
0
0
0
10
0
0
0
0
0
30
0
0
10
% E
% Phe:
0
0
30
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
40
10
0
0
0
0
30
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
30
90
0
0
20
0
0
0
10
0
0
10
% K
% Leu:
0
0
50
10
0
60
0
10
0
90
0
0
0
0
0
% L
% Met:
10
0
0
0
10
0
80
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
60
0
10
10
80
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
40
0
0
0
0
0
0
0
0
0
20
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
0
0
40
0
% R
% Ser:
0
0
0
0
0
0
0
30
0
0
0
30
0
30
0
% S
% Thr:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _