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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: S100A4 All Species: 33.94
Human Site: T15 Identified Species: 82.96
UniProt: P26447 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P26447 NP_002952.1 101 11729 T15 A L D V M V S T F H K Y S G K
Chimpanzee Pan troglodytes XP_513816 98 11125 T16 A L A V L V T T F H K Y S C Q
Rhesus Macaque Macaca mulatta XP_001110911 98 11116 T16 A L A V L V T T F H K Y S C Q
Dog Lupus familis XP_855158 97 10951 T15 A L A V M V S T F H K Y S G Q
Cat Felis silvestris
Mouse Mus musculus P07091 101 11703 T15 A L D V I V S T F H K Y S G K
Rat Rattus norvegicus P05942 101 11758 T15 A L D V I V S T F H K Y S G N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513231 101 11530 T15 A L E V M I S T F H K Y S G K
Chicken Gallus gallus Q98953 92 10257 T15 A I G L L V A T F H K Y S G K
Frog Xenopus laevis P27004 96 11311 M14 L E H S M E K M L L T F H K F
Zebra Danio Brachydanio rerio NP_997926 95 10388 T16 A M A M L I A T F H K Y S G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 61.3 61.3 61.3 N.A. 93 91 N.A. 74.2 47.5 32.6 53.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 78.2 78.2 78.2 N.A. 98 97 N.A. 88.1 66.3 58.4 68.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 66.6 66.6 86.6 N.A. 93.3 86.6 N.A. 86.6 66.6 6.6 60 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 86.6 86.6 93.3 N.A. 100 93.3 N.A. 100 93.3 13.3 93.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 90 0 40 0 0 0 20 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % C
% Asp: 0 0 30 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 10 10 0 0 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 90 0 0 10 0 0 10 % F
% Gly: 0 0 10 0 0 0 0 0 0 0 0 0 0 70 0 % G
% His: 0 0 10 0 0 0 0 0 0 90 0 0 10 0 0 % H
% Ile: 0 10 0 0 20 20 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 10 0 0 0 90 0 0 10 50 % K
% Leu: 10 70 0 10 40 0 0 0 10 10 0 0 0 0 0 % L
% Met: 0 10 0 10 40 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 30 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 10 0 0 50 0 0 0 0 0 90 0 0 % S
% Thr: 0 0 0 0 0 0 20 90 0 0 10 0 0 0 0 % T
% Val: 0 0 0 70 0 70 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 90 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _