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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
S100A4
All Species:
16.36
Human Site:
T39
Identified Species:
40
UniProt:
P26447
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26447
NP_002952.1
101
11729
T39
S
E
L
K
E
L
L
T
R
E
L
P
S
F
L
Chimpanzee
Pan troglodytes
XP_513816
98
11125
H40
G
E
M
K
E
L
L
H
K
E
L
P
S
F
V
Rhesus Macaque
Macaca mulatta
XP_001110911
98
11116
Q40
G
E
M
K
E
L
L
Q
K
E
L
P
S
F
V
Dog
Lupus familis
XP_855158
97
10951
Q39
A
E
M
K
T
L
L
Q
N
E
L
P
S
F
V
Cat
Felis silvestris
Mouse
Mus musculus
P07091
101
11703
T39
T
E
L
K
E
L
L
T
R
E
L
P
S
F
L
Rat
Rattus norvegicus
P05942
101
11758
T39
T
E
L
K
E
L
L
T
R
E
L
P
S
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513231
101
11530
T39
T
E
L
K
D
L
L
T
K
E
L
P
S
F
I
Chicken
Gallus gallus
Q98953
92
10257
Q39
G
E
L
K
E
L
I
Q
K
E
L
T
I
G
P
Frog
Xenopus laevis
P27004
96
11311
D38
D
D
L
Q
K
L
L
D
S
E
F
S
E
F
L
Zebra Danio
Brachydanio rerio
NP_997926
95
10388
S40
G
E
L
K
E
L
L
S
A
E
L
G
D
I
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.3
61.3
61.3
N.A.
93
91
N.A.
74.2
47.5
32.6
53.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
78.2
78.2
78.2
N.A.
98
97
N.A.
88.1
66.3
58.4
68.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
66.6
66.6
60
N.A.
93.3
93.3
N.A.
73.3
46.6
40
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
86.6
80
N.A.
100
100
N.A.
100
60
60
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
0
10
0
0
10
0
0
0
0
10
0
0
% D
% Glu:
0
90
0
0
70
0
0
0
0
100
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
80
10
% F
% Gly:
40
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
10
10
10
% I
% Lys:
0
0
0
90
10
0
0
0
40
0
0
0
0
0
0
% K
% Leu:
0
0
70
0
0
100
90
0
0
0
90
0
0
0
40
% L
% Met:
0
0
30
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
70
0
0
10
% P
% Gln:
0
0
0
10
0
0
0
30
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
30
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
0
0
10
10
0
0
10
70
0
0
% S
% Thr:
30
0
0
0
10
0
0
40
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
30
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _