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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HMGB2
All Species:
28.18
Human Site:
S107
Identified Species:
47.69
UniProt:
P26583
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26583
NP_001124160.1
209
24034
S107
S
A
F
F
L
F
C
S
E
H
R
P
K
I
K
Chimpanzee
Pan troglodytes
Q9N1Q7
215
24747
F132
K
R
P
P
L
A
F
F
L
F
C
S
E
Y
R
Rhesus Macaque
Macaca mulatta
XP_001085665
321
35536
S221
S
A
F
F
L
F
C
S
E
H
R
P
K
I
K
Dog
Lupus familis
XP_543194
210
24144
S107
S
A
F
F
L
F
C
S
E
H
R
P
K
I
K
Cat
Felis silvestris
Mouse
Mus musculus
P30681
210
24143
S107
S
A
F
F
L
F
C
S
E
N
R
P
K
I
K
Rat
Rattus norvegicus
P52925
210
24140
S107
S
A
F
F
L
F
C
S
E
H
R
P
K
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508702
215
24789
S107
S
A
F
F
L
F
C
S
E
Y
R
P
K
I
K
Chicken
Gallus gallus
P26584
207
23809
S107
S
A
F
F
L
F
C
S
E
H
R
P
K
I
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24537
393
44916
N283
S
A
F
F
W
F
C
N
D
E
R
N
K
V
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09390
235
27301
Q147
S
A
F
F
F
Y
S
Q
D
K
R
P
E
I
Q
Sea Urchin
Strong. purpuratus
P40644
200
22815
G112
S
A
F
F
I
F
S
G
E
N
R
A
A
I
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P27347
157
17127
A76
V
A
A
V
G
K
A
A
G
D
R
W
K
S
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11633
99
11557
T17
P
K
E
P
K
K
R
T
T
R
R
K
K
D
P
Red Bread Mold
Neurospora crassa
Q7S045
103
11590
D22
E
K
R
R
A
K
K
D
P
N
A
P
K
R
G
Conservation
Percent
Protein Identity:
100
56.7
64.4
98.5
N.A.
96.6
98.5
N.A.
78.1
91.3
N.A.
N.A.
N.A.
27.9
N.A.
34
48.3
Protein Similarity:
100
66.5
64.4
99.5
N.A.
99
99
N.A.
86.9
96.1
N.A.
N.A.
N.A.
38.6
N.A.
50.2
61.7
P-Site Identity:
100
6.6
100
100
N.A.
93.3
100
N.A.
93.3
100
N.A.
N.A.
N.A.
60
N.A.
46.6
60
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
N.A.
80
N.A.
73.3
73.3
Percent
Protein Identity:
N.A.
33.9
N.A.
N.A.
23.4
26.7
Protein Similarity:
N.A.
46.4
N.A.
N.A.
32
33.9
P-Site Identity:
N.A.
20
N.A.
N.A.
13.3
13.3
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
79
8
0
8
8
8
8
0
0
8
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
58
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
15
8
0
0
0
8
0
% D
% Glu:
8
0
8
0
0
0
0
0
58
8
0
0
15
0
0
% E
% Phe:
0
0
72
72
8
65
8
8
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
8
8
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
36
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
0
0
65
0
% I
% Lys:
8
15
0
0
8
22
8
0
0
8
0
8
79
0
65
% K
% Leu:
0
0
0
0
58
0
0
0
8
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
22
0
8
0
0
0
% N
% Pro:
8
0
8
15
0
0
0
0
8
0
0
65
0
0
8
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% Q
% Arg:
0
8
8
8
0
0
8
0
0
8
86
0
0
8
8
% R
% Ser:
72
0
0
0
0
0
15
50
0
0
0
8
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% T
% Val:
8
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
8
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _