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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HMGB2
All Species:
39.7
Human Site:
Y71
Identified Species:
67.18
UniProt:
P26583
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26583
NP_001124160.1
209
24034
Y71
A
K
S
D
K
A
R
Y
D
R
E
M
K
N
Y
Chimpanzee
Pan troglodytes
Q9N1Q7
215
24747
Y100
A
K
A
D
K
A
H
Y
E
R
E
M
K
T
Y
Rhesus Macaque
Macaca mulatta
XP_001085665
321
35536
Y185
A
K
S
D
K
A
R
Y
D
R
E
M
K
N
Y
Dog
Lupus familis
XP_543194
210
24144
Y71
A
K
S
D
K
A
R
Y
D
R
E
M
K
N
Y
Cat
Felis silvestris
Mouse
Mus musculus
P30681
210
24143
Y71
A
K
S
D
K
A
R
Y
D
R
E
M
K
N
Y
Rat
Rattus norvegicus
P52925
210
24140
Y71
A
K
S
D
K
A
R
Y
D
R
E
M
K
N
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508702
215
24789
Y71
A
K
A
D
K
V
R
Y
E
R
E
M
K
T
Y
Chicken
Gallus gallus
P26584
207
23809
Y71
A
K
G
D
K
A
R
Y
D
R
E
M
K
N
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24537
393
44916
Y241
A
E
K
D
K
Q
R
Y
E
A
E
M
Q
N
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09390
235
27301
Y107
A
Q
K
D
A
E
R
Y
Q
A
E
V
S
V
A
Sea Urchin
Strong. purpuratus
P40644
200
22815
Y73
S
M
R
D
K
V
R
Y
D
R
E
M
Q
S
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P27347
157
17127
A47
K
P
K
R
A
P
S
A
F
F
V
F
M
E
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11633
99
11557
Red Bread Mold
Neurospora crassa
Q7S045
103
11590
Conservation
Percent
Protein Identity:
100
56.7
64.4
98.5
N.A.
96.6
98.5
N.A.
78.1
91.3
N.A.
N.A.
N.A.
27.9
N.A.
34
48.3
Protein Similarity:
100
66.5
64.4
99.5
N.A.
99
99
N.A.
86.9
96.1
N.A.
N.A.
N.A.
38.6
N.A.
50.2
61.7
P-Site Identity:
100
73.3
100
100
N.A.
100
100
N.A.
73.3
93.3
N.A.
N.A.
N.A.
60
N.A.
33.3
60
P-Site Similarity:
100
86.6
100
100
N.A.
100
100
N.A.
86.6
93.3
N.A.
N.A.
N.A.
80
N.A.
46.6
80
Percent
Protein Identity:
N.A.
33.9
N.A.
N.A.
23.4
26.7
Protein Similarity:
N.A.
46.4
N.A.
N.A.
32
33.9
P-Site Identity:
N.A.
0
N.A.
N.A.
0
0
P-Site Similarity:
N.A.
0
N.A.
N.A.
0
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
72
0
15
0
15
50
0
8
0
15
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
79
0
0
0
0
50
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
0
8
0
0
22
0
79
0
0
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
8
0
8
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
58
22
0
72
0
0
0
0
0
0
0
58
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
72
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% N
% Pro:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
8
0
0
8
0
0
0
15
0
0
% Q
% Arg:
0
0
8
8
0
0
72
0
0
65
0
0
0
0
0
% R
% Ser:
8
0
36
0
0
0
8
0
0
0
0
0
8
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% T
% Val:
0
0
0
0
0
15
0
0
0
0
8
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
79
0
0
0
0
0
0
72
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _