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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTBP1 All Species: 28.79
Human Site: S262 Identified Species: 63.33
UniProt: P26599 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P26599 NP_002810.1 531 57221 S262 I D F S K L T S L N V K Y N N
Chimpanzee Pan troglodytes XP_001172084 934 99829 S639 I D F S K L T S L N V K Y N N
Rhesus Macaque Macaca mulatta XP_001092330 534 57473 X260 X X X X X X X X X X X X Y N N
Dog Lupus familis XP_868641 531 57131 S262 I D F S K L T S L N V K Y N N
Cat Felis silvestris
Mouse Mus musculus P17225 527 56460 S261 I D F S K L T S L N V K Y N N
Rat Rattus norvegicus Q00438 555 59335 S261 I D F S K L T S L N V K Y N N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506947 565 60769 S270 I D F S K L T S L N V K Y N N
Chicken Gallus gallus NP_001026106 526 56680 P258 P S G D N Q P P L D Q T M A A
Frog Xenopus laevis NP_001080169 547 59224 S259 I D F S K L T S L N V K Y N N
Zebra Danio Brachydanio rerio NP_001018313 574 61754 Y277 L T S L N V K Y N N D K S R D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q6ICX4 432 48215 C209 K G R S S H P C Y G D T G V A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 56.8 96.4 98.3 N.A. 92 92.6 N.A. 88.1 89.6 83.9 74.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 56.8 96.4 99.6 N.A. 93.7 94.5 N.A. 91.5 92.2 89.9 83 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 20 100 N.A. 100 100 N.A. 100 6.6 100 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 20 100 N.A. 100 100 N.A. 100 13.3 100 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 34.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 52.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 19 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 64 0 10 0 0 0 0 0 10 19 0 0 0 10 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 64 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 10 0 0 0 0 0 0 10 0 0 10 0 0 % G
% His: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % H
% Ile: 64 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 64 0 10 0 0 0 0 73 0 0 0 % K
% Leu: 10 0 0 10 0 64 0 0 73 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 0 0 19 0 0 0 10 73 0 0 0 73 73 % N
% Pro: 10 0 0 0 0 0 19 10 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 10 0 0 0 0 10 0 0 0 0 % Q
% Arg: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 0 % R
% Ser: 0 10 10 73 10 0 0 64 0 0 0 0 10 0 0 % S
% Thr: 0 10 0 0 0 0 64 0 0 0 0 19 0 0 0 % T
% Val: 0 0 0 0 0 10 0 0 0 0 64 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 10 10 0 0 0 73 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _