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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VARS All Species: 22.73
Human Site: S1120 Identified Species: 31.25
UniProt: P26640 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P26640 NP_006286.1 1264 140476 S1120 S I T R A V R S L R A D Y N L
Chimpanzee Pan troglodytes XP_001160008 1264 140384 S1120 S I T R A V R S L R A D Y N L
Rhesus Macaque Macaca mulatta Q5TM74 1064 118624 A967 G L L P P G A A A P S G W A Q
Dog Lupus familis XP_538837 1256 139671 T1120 L R A F Y N L T R I R P V C F
Cat Felis silvestris
Mouse Mus musculus Q9Z1Q9 1263 140197 S1119 S I T R A V R S L R A D Y N L
Rat Rattus norvegicus Q04462 1264 140350 S1120 S I T R A V R S L R A D Y N L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520676 985 109386 Q888 S P Q P T G A Q S L A D R W I
Chicken Gallus gallus
Frog Xenopus laevis NP_001088439 1243 140617 S1099 L I I K S I R S L R A D Y N L
Zebra Danio Brachydanio rerio XP_682807 1111 123867 L999 A L V Q K Y S L Q I Q T L S Y
Tiger Blowfish Takifugu rubipres P49696 1217 138200 S1073 G V V R T I R S L R S D Y K L
Fruit Fly Dros. melanogaster NP_524838 1049 118236 V952 T I S Y C S N V V F D S P A P
Honey Bee Apis mellifera XP_395202 1043 121057 T946 I E T L S Y S T L K T T Q P P
Nematode Worm Caenorhab. elegans Q9U1Q4 1050 118902 C953 K V S I L N K C E S D K I E K
Sea Urchin Strong. purpuratus XP_001200958 1119 126755 R1015 H P L A T L T R S S H V D I S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P93736 1108 125908 A1009 V V S K G Q H A A P P G S S V
Baker's Yeast Sacchar. cerevisiae P07806 1104 125751 E1001 S L I K A I D E V T V V R D A
Red Bread Mold Neurospora crassa P28350 1093 123334 A996 K E V N V L G A D E E L P R G
Conservation
Percent
Protein Identity: 100 99.5 43.4 92.8 N.A. 93.4 93.4 N.A. 63 N.A. 65.3 45 63.8 50.9 49.1 44.9 44.4
Protein Similarity: 100 99.8 56 95.6 N.A. 96.4 96.3 N.A. 69.8 N.A. 78 58.8 76.8 63.1 63.4 59.5 59.6
P-Site Identity: 100 100 0 0 N.A. 100 100 N.A. 20 N.A. 66.6 0 53.3 6.6 13.3 0 0
P-Site Similarity: 100 100 26.6 6.6 N.A. 100 100 N.A. 26.6 N.A. 86.6 26.6 73.3 26.6 33.3 20 6.6
Percent
Protein Identity: N.A. N.A. N.A. 41.6 42.6 40.3
Protein Similarity: N.A. N.A. N.A. 58.3 60.1 56
P-Site Identity: N.A. N.A. N.A. 0 13.3 0
P-Site Similarity: N.A. N.A. N.A. 40 46.6 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 6 6 30 0 12 18 12 0 36 0 0 12 6 % A
% Cys: 0 0 0 0 6 0 0 6 0 0 0 0 0 6 0 % C
% Asp: 0 0 0 0 0 0 6 0 6 0 12 42 6 6 0 % D
% Glu: 0 12 0 0 0 0 0 6 6 6 6 0 0 6 0 % E
% Phe: 0 0 0 6 0 0 0 0 0 6 0 0 0 0 6 % F
% Gly: 12 0 0 0 6 12 6 0 0 0 0 12 0 0 6 % G
% His: 6 0 0 0 0 0 6 0 0 0 6 0 0 0 0 % H
% Ile: 6 36 12 6 0 18 0 0 0 12 0 0 6 6 6 % I
% Lys: 12 0 0 18 6 0 6 0 0 6 0 6 0 6 6 % K
% Leu: 12 18 12 6 6 12 6 6 42 6 0 6 6 0 36 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 6 0 12 6 0 0 0 0 0 0 30 0 % N
% Pro: 0 12 0 12 6 0 0 0 0 12 6 6 12 6 12 % P
% Gln: 0 0 6 6 0 6 0 6 6 0 6 0 6 0 6 % Q
% Arg: 0 6 0 30 0 0 36 6 6 36 6 0 12 6 0 % R
% Ser: 36 0 18 0 12 6 12 36 12 12 12 6 6 12 6 % S
% Thr: 6 0 30 0 18 0 6 12 0 6 6 12 0 0 0 % T
% Val: 6 18 18 0 6 24 0 6 12 0 6 12 6 0 6 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 6 6 0 % W
% Tyr: 0 0 0 6 6 12 0 0 0 0 0 0 36 0 6 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _