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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VARS
All Species:
11.82
Human Site:
S140
Identified Species:
16.25
UniProt:
P26640
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26640
NP_006286.1
1264
140476
S140
G
A
L
G
R
A
L
S
P
L
E
E
W
L
R
Chimpanzee
Pan troglodytes
XP_001160008
1264
140384
S140
G
A
L
G
R
A
L
S
P
L
E
E
W
L
R
Rhesus Macaque
Macaca mulatta
Q5TM74
1064
118624
K93
I
P
T
K
P
G
E
K
K
D
V
S
G
P
L
Dog
Lupus familis
XP_538837
1256
139671
S140
G
A
L
G
R
A
L
S
P
L
E
E
W
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1Q9
1263
140197
N140
G
A
L
G
K
A
L
N
P
L
E
D
W
L
R
Rat
Rattus norvegicus
Q04462
1264
140350
N140
G
A
L
G
K
A
L
N
P
L
E
E
W
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520676
985
109386
S15
P
H
P
E
S
F
P
S
L
R
A
L
I
A
A
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088439
1243
140617
K126
D
N
L
D
C
Y
L
K
L
R
T
Y
L
V
G
Zebra Danio
Brachydanio rerio
XP_682807
1111
123867
P125
D
L
T
H
G
S
V
P
G
Y
N
S
Q
R
V
Tiger Blowfish
Takifugu rubipres
P49696
1217
138200
M124
P
S
D
R
N
V
L
M
N
V
T
R
W
F
T
Fruit Fly
Dros. melanogaster
NP_524838
1049
118236
A79
A
V
Y
T
A
Q
T
A
P
G
E
K
K
D
L
Honey Bee
Apis mellifera
XP_395202
1043
121057
N73
E
L
A
I
Y
T
I
N
T
L
E
G
D
K
K
Nematode Worm
Caenorhab. elegans
Q9U1Q4
1050
118902
P80
K
K
I
D
G
E
I
P
A
A
Y
F
P
G
Y
Sea Urchin
Strong. purpuratus
XP_001200958
1119
126755
Q131
S
R
R
Q
G
A
G
Q
K
S
W
S
K
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93736
1108
125908
T124
E
D
F
V
D
P
E
T
P
L
G
E
R
K
R
Baker's Yeast
Sacchar. cerevisiae
P07806
1104
125751
E124
K
E
V
E
P
I
P
E
F
I
D
K
T
V
P
Red Bread Mold
Neurospora crassa
P28350
1093
123334
T121
L
P
P
Y
E
D
S
T
P
A
G
E
K
K
V
Conservation
Percent
Protein Identity:
100
99.5
43.4
92.8
N.A.
93.4
93.4
N.A.
63
N.A.
65.3
45
63.8
50.9
49.1
44.9
44.4
Protein Similarity:
100
99.8
56
95.6
N.A.
96.4
96.3
N.A.
69.8
N.A.
78
58.8
76.8
63.1
63.4
59.5
59.6
P-Site Identity:
100
100
0
100
N.A.
80
86.6
N.A.
6.6
N.A.
13.3
0
13.3
13.3
13.3
0
6.6
P-Site Similarity:
100
100
0
100
N.A.
100
100
N.A.
6.6
N.A.
20
13.3
26.6
26.6
33.3
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.6
42.6
40.3
Protein Similarity:
N.A.
N.A.
N.A.
58.3
60.1
56
P-Site Identity:
N.A.
N.A.
N.A.
26.6
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
30
6
0
6
36
0
6
6
12
6
0
0
6
6
% A
% Cys:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
6
6
12
6
6
0
0
0
6
6
6
6
6
0
% D
% Glu:
12
6
0
12
6
6
12
6
0
0
42
36
0
0
6
% E
% Phe:
0
0
6
0
0
6
0
0
6
0
0
6
0
6
0
% F
% Gly:
30
0
0
30
18
6
6
0
6
6
12
6
6
6
6
% G
% His:
0
6
0
6
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
6
0
6
6
0
6
12
0
0
6
0
0
6
0
0
% I
% Lys:
12
6
0
6
12
0
0
12
12
0
0
12
18
24
6
% K
% Leu:
6
12
36
0
0
0
42
0
12
42
0
6
6
30
12
% L
% Met:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% M
% Asn:
0
6
0
0
6
0
0
18
6
0
6
0
0
0
0
% N
% Pro:
12
12
12
0
12
6
12
12
48
0
0
0
6
6
6
% P
% Gln:
0
0
0
6
0
6
0
6
0
0
0
0
6
0
0
% Q
% Arg:
0
6
6
6
18
0
0
0
0
12
0
6
6
6
36
% R
% Ser:
6
6
0
0
6
6
6
24
0
6
0
18
0
0
0
% S
% Thr:
0
0
12
6
0
6
6
12
6
0
12
0
6
0
6
% T
% Val:
0
6
6
6
0
6
6
0
0
6
6
0
0
12
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
6
0
36
0
0
% W
% Tyr:
0
0
6
6
6
6
0
0
0
6
6
6
0
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _