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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VARS
All Species:
14.85
Human Site:
S217
Identified Species:
20.42
UniProt:
P26640
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26640
NP_006286.1
1264
140476
S217
Y
S
G
A
R
P
L
S
H
Q
P
G
P
E
A
Chimpanzee
Pan troglodytes
XP_001160008
1264
140384
S217
Y
S
G
A
R
P
L
S
H
Q
P
G
P
E
A
Rhesus Macaque
Macaca mulatta
Q5TM74
1064
118624
R168
A
I
Q
D
A
L
V
R
W
H
R
M
R
G
D
Dog
Lupus familis
XP_538837
1256
139671
S217
Y
S
G
A
R
L
L
S
Q
Q
P
G
P
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1Q9
1263
140197
T217
Y
S
G
A
R
S
V
T
Q
Q
P
G
S
E
V
Rat
Rattus norvegicus
Q04462
1264
140350
T217
Y
S
G
A
R
S
V
T
Q
Q
P
G
S
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520676
985
109386
N90
T
L
V
Q
Q
W
V
N
Y
A
D
G
E
L
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088439
1243
140617
P206
S
N
G
P
S
G
S
P
I
S
G
P
P
K
T
Zebra Danio
Brachydanio rerio
XP_682807
1111
123867
N200
L
Q
S
G
Y
L
S
N
I
Q
Q
C
P
A
Q
Tiger Blowfish
Takifugu rubipres
P49696
1217
138200
K200
K
L
E
K
F
Q
Q
K
K
E
M
E
A
K
K
Fruit Fly
Dros. melanogaster
NP_524838
1049
118236
I154
G
H
A
L
T
N
A
I
E
D
A
I
T
R
Y
Honey Bee
Apis mellifera
XP_395202
1043
121057
N148
H
L
G
H
A
L
T
N
A
V
E
D
A
I
T
Nematode Worm
Caenorhab. elegans
Q9U1Q4
1050
118902
G155
T
R
F
N
R
M
H
G
K
R
T
L
F
N
P
Sea Urchin
Strong. purpuratus
XP_001200958
1119
126755
P206
F
V
M
C
L
P
P
P
N
V
T
G
V
L
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93736
1108
125908
R199
A
I
E
D
T
I
I
R
W
K
R
M
S
G
Y
Baker's Yeast
Sacchar. cerevisiae
P07806
1104
125751
G199
V
T
G
A
L
H
I
G
H
A
L
T
I
A
I
Red Bread Mold
Neurospora crassa
P28350
1093
123334
Q196
H
A
L
A
N
S
L
Q
D
T
L
I
R
W
Y
Conservation
Percent
Protein Identity:
100
99.5
43.4
92.8
N.A.
93.4
93.4
N.A.
63
N.A.
65.3
45
63.8
50.9
49.1
44.9
44.4
Protein Similarity:
100
99.8
56
95.6
N.A.
96.4
96.3
N.A.
69.8
N.A.
78
58.8
76.8
63.1
63.4
59.5
59.6
P-Site Identity:
100
100
0
80
N.A.
60
60
N.A.
6.6
N.A.
13.3
13.3
0
0
6.6
6.6
13.3
P-Site Similarity:
100
100
6.6
80
N.A.
73.3
73.3
N.A.
33.3
N.A.
26.6
20
13.3
0
20
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.6
42.6
40.3
Protein Similarity:
N.A.
N.A.
N.A.
58.3
60.1
56
P-Site Identity:
N.A.
N.A.
N.A.
0
20
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
33.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
6
6
42
12
0
6
0
6
12
6
0
12
12
12
% A
% Cys:
0
0
0
6
0
0
0
0
0
0
0
6
0
0
0
% C
% Asp:
0
0
0
12
0
0
0
0
6
6
6
6
0
0
6
% D
% Glu:
0
0
12
0
0
0
0
0
6
6
6
6
6
30
0
% E
% Phe:
6
0
6
0
6
0
0
0
0
0
0
0
6
0
0
% F
% Gly:
6
0
48
6
0
6
0
12
0
0
6
42
0
12
0
% G
% His:
12
6
0
6
0
6
6
0
18
6
0
0
0
0
6
% H
% Ile:
0
12
0
0
0
6
12
6
12
0
0
12
6
6
12
% I
% Lys:
6
0
0
6
0
0
0
6
12
6
0
0
0
12
6
% K
% Leu:
6
18
6
6
12
24
24
0
0
0
12
6
0
12
0
% L
% Met:
0
0
6
0
0
6
0
0
0
0
6
12
0
0
0
% M
% Asn:
0
6
0
6
6
6
0
18
6
0
0
0
0
6
0
% N
% Pro:
0
0
0
6
0
18
6
12
0
0
30
6
30
0
6
% P
% Gln:
0
6
6
6
6
6
6
6
18
36
6
0
0
0
6
% Q
% Arg:
0
6
0
0
36
0
0
12
0
6
12
0
12
6
0
% R
% Ser:
6
30
6
0
6
18
12
18
0
6
0
0
18
0
0
% S
% Thr:
12
6
0
0
12
0
6
12
0
6
12
6
6
0
12
% T
% Val:
6
6
6
0
0
0
24
0
0
12
0
0
6
0
18
% V
% Trp:
0
0
0
0
0
6
0
0
12
0
0
0
0
6
0
% W
% Tyr:
30
0
0
0
6
0
0
0
6
0
0
0
0
0
18
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _