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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VARS
All Species:
31.21
Human Site:
S349
Identified Species:
42.92
UniProt:
P26640
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26640
NP_006286.1
1264
140476
S349
P
P
P
N
V
T
G
S
L
H
L
G
H
A
L
Chimpanzee
Pan troglodytes
XP_001160008
1264
140384
S349
P
P
P
N
V
T
G
S
L
H
L
G
H
A
L
Rhesus Macaque
Macaca mulatta
Q5TM74
1064
118624
R263
A
V
T
E
A
F
V
R
L
Y
K
A
G
L
L
Dog
Lupus familis
XP_538837
1256
139671
S349
P
P
P
N
V
T
G
S
L
H
L
G
H
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1Q9
1263
140197
S348
P
P
P
N
V
T
G
S
L
H
L
G
H
A
L
Rat
Rattus norvegicus
Q04462
1264
140350
S349
P
P
P
N
V
T
G
S
L
H
L
G
H
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520676
985
109386
H185
R
W
F
L
A
C
V
H
Q
P
Q
F
Q
A
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088439
1243
140617
S330
P
P
P
N
V
T
G
S
L
H
L
G
H
A
L
Zebra Danio
Brachydanio rerio
XP_682807
1111
123867
K295
Q
W
L
I
V
K
N
K
A
I
I
G
P
K
C
Tiger Blowfish
Takifugu rubipres
P49696
1217
138200
S298
P
P
P
N
V
T
G
S
L
H
L
G
H
A
L
Fruit Fly
Dros. melanogaster
NP_524838
1049
118236
V249
D
P
K
L
C
R
A
V
T
E
A
F
V
R
L
Honey Bee
Apis mellifera
XP_395202
1043
121057
R243
T
M
D
P
K
L
C
R
A
V
S
E
A
F
I
Nematode Worm
Caenorhab. elegans
Q9U1Q4
1050
118902
T250
I
R
M
H
E
S
G
T
I
Y
R
S
N
R
L
Sea Urchin
Strong. purpuratus
XP_001200958
1119
126755
N306
S
L
D
W
D
R
D
N
F
T
M
D
Q
K
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93736
1108
125908
R294
A
V
T
E
A
F
V
R
L
Y
K
E
G
L
I
Baker's Yeast
Sacchar. cerevisiae
P07806
1104
125751
S294
S
R
E
A
F
T
L
S
P
E
L
T
K
S
V
Red Bread Mold
Neurospora crassa
P28350
1093
123334
M291
K
N
L
T
A
A
T
M
E
T
F
C
R
L
H
Conservation
Percent
Protein Identity:
100
99.5
43.4
92.8
N.A.
93.4
93.4
N.A.
63
N.A.
65.3
45
63.8
50.9
49.1
44.9
44.4
Protein Similarity:
100
99.8
56
95.6
N.A.
96.4
96.3
N.A.
69.8
N.A.
78
58.8
76.8
63.1
63.4
59.5
59.6
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
6.6
N.A.
100
13.3
100
13.3
0
13.3
0
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
13.3
N.A.
100
20
100
13.3
6.6
53.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.6
42.6
40.3
Protein Similarity:
N.A.
N.A.
N.A.
58.3
60.1
56
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
0
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
6
24
6
6
0
12
0
6
6
6
48
0
% A
% Cys:
0
0
0
0
6
6
6
0
0
0
0
6
0
0
6
% C
% Asp:
6
0
12
0
6
0
6
0
0
0
0
6
0
0
0
% D
% Glu:
0
0
6
12
6
0
0
0
6
12
0
12
0
0
0
% E
% Phe:
0
0
6
0
6
12
0
0
6
0
6
12
0
6
6
% F
% Gly:
0
0
0
0
0
0
48
0
0
0
0
48
12
0
0
% G
% His:
0
0
0
6
0
0
0
6
0
42
0
0
42
0
6
% H
% Ile:
6
0
0
6
0
0
0
0
6
6
6
0
0
0
12
% I
% Lys:
6
0
6
0
6
6
0
6
0
0
12
0
6
12
0
% K
% Leu:
0
6
12
12
0
6
6
0
53
0
48
0
0
18
59
% L
% Met:
0
6
6
0
0
0
0
6
0
0
6
0
0
0
0
% M
% Asn:
0
6
0
42
0
0
6
6
0
0
0
0
6
0
0
% N
% Pro:
42
48
42
6
0
0
0
0
6
6
0
0
6
0
0
% P
% Gln:
6
0
0
0
0
0
0
0
6
0
6
0
12
0
0
% Q
% Arg:
6
12
0
0
0
12
0
18
0
0
6
0
6
12
0
% R
% Ser:
12
0
0
0
0
6
0
48
0
0
6
6
0
6
0
% S
% Thr:
6
0
12
6
0
48
6
6
6
12
0
6
0
0
0
% T
% Val:
0
12
0
0
48
0
18
6
0
6
0
0
6
0
12
% V
% Trp:
0
12
0
6
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
18
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _