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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VARS
All Species:
29.7
Human Site:
S436
Identified Species:
40.83
UniProt:
P26640
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26640
NP_006286.1
1264
140476
S436
H
Q
L
K
K
L
G
S
S
L
D
W
D
R
A
Chimpanzee
Pan troglodytes
XP_001160008
1264
140384
S436
H
Q
L
K
K
L
G
S
S
L
D
W
D
R
A
Rhesus Macaque
Macaca mulatta
Q5TM74
1064
118624
P340
V
V
V
G
T
T
R
P
E
T
L
P
G
D
V
Dog
Lupus familis
XP_538837
1256
139671
S436
H
Q
L
K
K
L
G
S
S
L
D
W
N
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1Q9
1263
140197
S435
H
Q
L
K
K
L
G
S
S
L
D
W
D
R
A
Rat
Rattus norvegicus
Q04462
1264
140350
S436
H
Q
L
K
K
L
G
S
S
L
D
W
D
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520676
985
109386
K262
P
K
A
E
K
K
E
K
R
D
P
G
V
I
T
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088439
1243
140617
S417
H
Q
L
R
I
L
G
S
S
L
D
W
D
R
A
Zebra Danio
Brachydanio rerio
XP_682807
1111
123867
L372
G
C
L
D
F
G
D
L
V
E
G
S
T
K
A
Tiger Blowfish
Takifugu rubipres
P49696
1217
138200
S385
H
Q
L
K
K
L
G
S
S
L
D
W
D
R
A
Fruit Fly
Dros. melanogaster
NP_524838
1049
118236
A326
S
D
E
E
I
I
V
A
T
T
R
I
E
T
M
Honey Bee
Apis mellifera
XP_395202
1043
121057
I320
I
D
F
E
K
K
I
I
V
A
T
T
R
I
E
Nematode Worm
Caenorhab. elegans
Q9U1Q4
1050
118902
G327
E
T
M
L
G
D
S
G
V
A
V
H
P
D
D
Sea Urchin
Strong. purpuratus
XP_001200958
1119
126755
E385
T
Y
F
A
Y
P
I
E
S
S
D
A
E
I
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93736
1108
125908
T371
V
A
T
T
R
V
E
T
M
L
G
D
T
A
I
Baker's Yeast
Sacchar. cerevisiae
P07806
1104
125751
D372
A
Y
P
V
I
G
S
D
E
K
L
I
I
A
T
Red Bread Mold
Neurospora crassa
P28350
1093
123334
T368
E
E
T
I
E
V
A
T
T
R
P
E
T
M
L
Conservation
Percent
Protein Identity:
100
99.5
43.4
92.8
N.A.
93.4
93.4
N.A.
63
N.A.
65.3
45
63.8
50.9
49.1
44.9
44.4
Protein Similarity:
100
99.8
56
95.6
N.A.
96.4
96.3
N.A.
69.8
N.A.
78
58.8
76.8
63.1
63.4
59.5
59.6
P-Site Identity:
100
100
0
93.3
N.A.
100
100
N.A.
6.6
N.A.
86.6
13.3
100
0
6.6
0
13.3
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
20
N.A.
93.3
20
100
33.3
13.3
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.6
42.6
40.3
Protein Similarity:
N.A.
N.A.
N.A.
58.3
60.1
56
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
0
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
6
6
0
0
6
6
0
12
0
6
0
12
48
% A
% Cys:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
6
0
6
6
6
0
6
48
6
36
12
6
% D
% Glu:
12
6
6
18
6
0
12
6
12
6
0
6
12
0
6
% E
% Phe:
0
0
12
0
6
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
6
0
0
6
6
12
42
6
0
0
12
6
6
0
0
% G
% His:
42
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% H
% Ile:
6
0
0
6
18
6
12
6
0
0
0
12
6
18
6
% I
% Lys:
0
6
0
36
48
12
0
6
0
6
0
0
0
6
0
% K
% Leu:
0
0
48
6
0
42
0
6
0
48
12
0
0
0
6
% L
% Met:
0
0
6
0
0
0
0
0
6
0
0
0
0
6
6
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% N
% Pro:
6
0
6
0
0
6
0
6
0
0
12
6
6
0
0
% P
% Gln:
0
42
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
6
6
0
6
0
6
6
6
0
6
42
0
% R
% Ser:
6
0
0
0
0
0
12
42
48
6
0
6
0
0
0
% S
% Thr:
6
6
12
6
6
6
0
12
12
12
6
6
18
6
12
% T
% Val:
12
6
6
6
0
12
6
0
18
0
6
0
6
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
42
0
0
0
% W
% Tyr:
0
12
0
0
6
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _