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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VARS
All Species:
24.55
Human Site:
S525
Identified Species:
33.75
UniProt:
P26640
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26640
NP_006286.1
1264
140476
S525
F
A
Y
K
V
Q
G
S
D
S
D
E
E
V
V
Chimpanzee
Pan troglodytes
XP_001160008
1264
140384
S525
F
A
Y
K
V
Q
G
S
D
S
D
E
E
V
V
Rhesus Macaque
Macaca mulatta
Q5TM74
1064
118624
D429
T
M
T
S
L
C
G
D
W
L
Q
G
L
H
R
Dog
Lupus familis
XP_538837
1256
139671
S525
F
A
Y
K
I
Q
G
S
D
G
D
E
E
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1Q9
1263
140197
S524
F
A
Y
K
V
Q
G
S
D
S
D
E
E
V
V
Rat
Rattus norvegicus
Q04462
1264
140350
S525
F
A
Y
K
V
Q
G
S
D
S
D
E
E
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520676
985
109386
Q351
H
A
L
T
N
A
I
Q
D
A
L
T
R
W
H
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088439
1243
140617
T506
F
A
Y
K
V
Q
E
T
G
E
E
I
V
V
A
Zebra Danio
Brachydanio rerio
XP_682807
1111
123867
N461
F
I
N
I
L
D
E
N
G
L
L
I
N
V
P
Tiger Blowfish
Takifugu rubipres
P49696
1217
138200
S474
F
A
Y
K
V
D
G
S
D
E
E
V
V
V
A
Fruit Fly
Dros. melanogaster
NP_524838
1049
118236
G415
N
D
D
G
Y
I
I
G
D
Y
G
E
F
T
G
Honey Bee
Apis mellifera
XP_395202
1043
121057
V409
I
F
D
D
T
G
N
V
I
G
D
Y
G
Q
F
Nematode Worm
Caenorhab. elegans
Q9U1Q4
1050
118902
F416
E
F
S
G
M
K
R
F
D
A
R
T
A
V
I
Sea Urchin
Strong. purpuratus
XP_001200958
1119
126755
V474
H
D
L
D
S
L
N
V
I
D
E
E
G
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93736
1108
125908
D460
I
N
T
N
G
G
S
D
F
A
G
M
P
R
F
Baker's Yeast
Sacchar. cerevisiae
P07806
1104
125751
T461
L
E
F
I
N
I
L
T
D
D
G
L
L
N
E
Red Bread Mold
Neurospora crassa
P28350
1093
123334
N457
E
N
G
T
L
N
D
N
A
G
P
F
K
G
Q
Conservation
Percent
Protein Identity:
100
99.5
43.4
92.8
N.A.
93.4
93.4
N.A.
63
N.A.
65.3
45
63.8
50.9
49.1
44.9
44.4
Protein Similarity:
100
99.8
56
95.6
N.A.
96.4
96.3
N.A.
69.8
N.A.
78
58.8
76.8
63.1
63.4
59.5
59.6
P-Site Identity:
100
100
6.6
86.6
N.A.
100
100
N.A.
13.3
N.A.
46.6
13.3
60
13.3
6.6
13.3
6.6
P-Site Similarity:
100
100
13.3
93.3
N.A.
100
100
N.A.
20
N.A.
60
26.6
66.6
13.3
6.6
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.6
42.6
40.3
Protein Similarity:
N.A.
N.A.
N.A.
58.3
60.1
56
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
48
0
0
0
6
0
0
6
18
0
0
6
0
12
% A
% Cys:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
12
12
0
12
6
12
59
12
36
0
0
0
0
% D
% Glu:
12
6
0
0
0
0
12
0
0
12
18
42
30
0
6
% E
% Phe:
48
12
6
0
0
0
0
6
6
0
0
6
6
0
12
% F
% Gly:
0
0
6
12
6
12
42
6
12
18
18
6
12
6
6
% G
% His:
12
0
0
0
0
0
0
0
0
0
0
0
0
6
6
% H
% Ile:
12
6
0
12
6
12
12
0
12
0
0
12
0
0
12
% I
% Lys:
0
0
0
42
0
6
0
0
0
0
0
0
6
6
0
% K
% Leu:
6
0
12
0
18
6
6
0
0
12
12
6
12
0
0
% L
% Met:
0
6
0
0
6
0
0
0
0
0
0
6
0
0
0
% M
% Asn:
6
12
6
6
12
6
12
12
0
0
0
0
6
6
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
6
0
6
0
6
% P
% Gln:
0
0
0
0
0
36
0
6
0
0
6
0
0
6
6
% Q
% Arg:
0
0
0
0
0
0
6
0
0
0
6
0
6
6
6
% R
% Ser:
0
0
6
6
6
0
6
36
0
24
0
0
0
0
0
% S
% Thr:
6
0
12
12
6
0
0
12
0
0
0
12
0
6
0
% T
% Val:
0
0
0
0
36
0
0
12
0
0
0
6
12
53
30
% V
% Trp:
0
0
0
0
0
0
0
0
6
0
0
0
0
6
0
% W
% Tyr:
0
0
42
0
6
0
0
0
0
6
0
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _