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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VARS
All Species:
26.97
Human Site:
T279
Identified Species:
37.08
UniProt:
P26640
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26640
NP_006286.1
1264
140476
T279
K
R
D
P
G
V
I
T
Y
D
L
P
T
P
P
Chimpanzee
Pan troglodytes
XP_001160008
1264
140384
T279
K
R
D
P
G
V
I
T
Y
D
L
P
T
P
P
Rhesus Macaque
Macaca mulatta
Q5TM74
1064
118624
K196
A
T
Q
A
V
V
E
K
Q
L
W
K
E
Q
G
Dog
Lupus familis
XP_538837
1256
139671
T279
K
R
D
P
G
V
I
T
Y
D
L
P
T
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1Q9
1263
140197
T278
K
R
D
P
G
V
I
T
Y
D
L
P
T
P
P
Rat
Rattus norvegicus
Q04462
1264
140350
T279
K
R
D
P
G
V
I
T
Y
D
L
P
T
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520676
985
109386
Q118
A
R
P
G
G
D
S
Q
A
A
I
A
A
L
G
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088439
1243
140617
T260
K
K
E
I
G
V
I
T
Y
D
I
P
T
P
A
Zebra Danio
Brachydanio rerio
XP_682807
1111
123867
A228
S
W
T
T
G
D
L
A
D
I
R
T
Q
V
L
Tiger Blowfish
Takifugu rubipres
P49696
1217
138200
T228
K
R
E
L
G
V
I
T
Y
D
I
P
T
P
S
Fruit Fly
Dros. melanogaster
NP_524838
1049
118236
T182
C
D
H
A
G
I
A
T
Q
V
V
V
E
K
L
Honey Bee
Apis mellifera
XP_395202
1043
121057
I176
P
G
C
D
H
A
G
I
A
T
Q
V
V
V
E
Nematode Worm
Caenorhab. elegans
Q9U1Q4
1050
118902
R183
E
K
R
L
K
R
E
R
G
L
T
R
H
D
L
Sea Urchin
Strong. purpuratus
XP_001200958
1119
126755
V235
R
W
K
R
M
V
G
V
P
S
L
W
I
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93736
1108
125908
K227
A
T
Q
V
V
V
E
K
K
I
M
R
D
R
G
Baker's Yeast
Sacchar. cerevisiae
P07806
1104
125751
F227
T
V
L
F
L
P
G
F
D
H
A
G
I
A
T
Red Bread Mold
Neurospora crassa
P28350
1093
123334
Q224
D
H
A
G
I
S
T
Q
S
V
V
E
K
M
L
Conservation
Percent
Protein Identity:
100
99.5
43.4
92.8
N.A.
93.4
93.4
N.A.
63
N.A.
65.3
45
63.8
50.9
49.1
44.9
44.4
Protein Similarity:
100
99.8
56
95.6
N.A.
96.4
96.3
N.A.
69.8
N.A.
78
58.8
76.8
63.1
63.4
59.5
59.6
P-Site Identity:
100
100
6.6
93.3
N.A.
100
100
N.A.
13.3
N.A.
66.6
6.6
73.3
13.3
0
0
20
P-Site Similarity:
100
100
6.6
93.3
N.A.
100
100
N.A.
20
N.A.
86.6
13.3
86.6
26.6
0
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.6
42.6
40.3
Protein Similarity:
N.A.
N.A.
N.A.
58.3
60.1
56
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
0
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
18
0
6
12
0
6
6
6
12
6
6
6
6
6
12
% A
% Cys:
6
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
6
30
6
0
12
0
0
12
42
0
0
6
6
0
% D
% Glu:
6
0
12
0
0
0
18
0
0
0
0
6
12
0
6
% E
% Phe:
0
0
0
6
0
0
0
6
0
0
0
0
0
0
0
% F
% Gly:
0
6
0
12
59
0
18
0
6
0
0
6
0
0
24
% G
% His:
0
6
6
0
6
0
0
0
0
6
0
0
6
0
0
% H
% Ile:
0
0
0
6
6
6
42
6
0
12
18
0
12
0
0
% I
% Lys:
42
12
6
0
6
0
0
12
6
0
0
6
6
6
0
% K
% Leu:
0
0
6
12
6
0
6
0
0
12
36
0
0
6
24
% L
% Met:
0
0
0
0
6
0
0
0
0
0
6
0
0
6
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
6
0
6
30
0
6
0
0
6
0
0
42
0
48
24
% P
% Gln:
0
0
12
0
0
0
0
12
12
0
6
0
6
6
0
% Q
% Arg:
6
42
6
6
0
6
0
6
0
0
6
12
0
6
0
% R
% Ser:
6
0
0
0
0
6
6
0
6
6
0
0
0
0
6
% S
% Thr:
6
12
6
6
0
0
6
48
0
6
6
6
42
0
6
% T
% Val:
0
6
0
6
12
59
0
6
0
12
12
12
6
12
0
% V
% Trp:
0
12
0
0
0
0
0
0
0
0
6
6
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
42
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _