Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VARS All Species: 27.88
Human Site: T789 Identified Species: 38.33
UniProt: P26640 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P26640 NP_006286.1 1264 140476 T789 Q D E D V L D T W F S S G L F
Chimpanzee Pan troglodytes XP_001160008 1264 140384 T789 Q D E D V L D T W F S S G L F
Rhesus Macaque Macaca mulatta Q5TM74 1064 118624 Q656 H P M V R D R Q G R K M S K S
Dog Lupus familis XP_538837 1256 139671 T789 Q D E D V L D T W F S S G L F
Cat Felis silvestris
Mouse Mus musculus Q9Z1Q9 1263 140197 T788 Q D E D V L D T W F S S G L F
Rat Rattus norvegicus Q04462 1264 140350 T789 Q D E D V L D T W F S S G L F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520676 985 109386 G578 V D M E F G T G A V K I T P A
Chicken Gallus gallus
Frog Xenopus laevis NP_001088439 1243 140617 T768 Q D E D V L D T W F S S G I F
Zebra Danio Brachydanio rerio XP_682807 1111 123867 P688 L K L T G K L P F K E V Y L H
Tiger Blowfish Takifugu rubipres P49696 1217 138200 T736 Q D E D V L D T W F S S G I N
Fruit Fly Dros. melanogaster NP_524838 1049 118236 Y642 K L P F K E V Y L H P M V R D
Honey Bee Apis mellifera XP_395202 1043 121057 Y636 K L P F K E V Y L H A M V R D
Nematode Worm Caenorhab. elegans Q9U1Q4 1050 118902 M643 R D A H G R K M S K S L G N V
Sea Urchin Strong. purpuratus XP_001200958 1119 126755 K702 T G E L P F H K V Y L H S M V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P93736 1108 125908 R689 V Y F H P M I R D A H G R K M
Baker's Yeast Sacchar. cerevisiae P07806 1104 125751 K688 L T G S V P F K E V F C H S L
Red Bread Mold Neurospora crassa P28350 1093 123334 R686 V Y C H S L I R D S E G R K M
Conservation
Percent
Protein Identity: 100 99.5 43.4 92.8 N.A. 93.4 93.4 N.A. 63 N.A. 65.3 45 63.8 50.9 49.1 44.9 44.4
Protein Similarity: 100 99.8 56 95.6 N.A. 96.4 96.3 N.A. 69.8 N.A. 78 58.8 76.8 63.1 63.4 59.5 59.6
P-Site Identity: 100 100 0 100 N.A. 100 100 N.A. 6.6 N.A. 93.3 6.6 86.6 0 0 20 6.6
P-Site Similarity: 100 100 0 100 N.A. 100 100 N.A. 13.3 N.A. 100 13.3 93.3 6.6 13.3 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. 41.6 42.6 40.3
Protein Similarity: N.A. N.A. N.A. 58.3 60.1 56
P-Site Identity: N.A. N.A. N.A. 0 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. 6.6 6.6 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 6 0 0 0 0 0 6 6 6 0 0 0 6 % A
% Cys: 0 0 6 0 0 0 0 0 0 0 0 6 0 0 0 % C
% Asp: 0 53 0 42 0 6 42 0 12 0 0 0 0 0 12 % D
% Glu: 0 0 48 6 0 12 0 0 6 0 12 0 0 0 0 % E
% Phe: 0 0 6 12 6 6 6 0 6 42 6 0 0 0 36 % F
% Gly: 0 6 6 0 12 6 0 6 6 0 0 12 48 0 0 % G
% His: 6 0 0 18 0 0 6 0 0 12 6 6 6 0 6 % H
% Ile: 0 0 0 0 0 0 12 0 0 0 0 6 0 12 0 % I
% Lys: 12 6 0 0 12 6 6 12 0 12 12 0 0 18 0 % K
% Leu: 12 12 6 6 0 48 6 0 12 0 6 6 0 36 6 % L
% Met: 0 0 12 0 0 6 0 6 0 0 0 18 0 6 12 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 6 % N
% Pro: 0 6 12 0 12 6 0 6 0 0 6 0 0 6 0 % P
% Gln: 42 0 0 0 0 0 0 6 0 0 0 0 0 0 0 % Q
% Arg: 6 0 0 0 6 6 6 12 0 6 0 0 12 12 0 % R
% Ser: 0 0 0 6 6 0 0 0 6 6 48 42 12 6 6 % S
% Thr: 6 6 0 6 0 0 6 42 0 0 0 0 6 0 0 % T
% Val: 18 0 0 6 48 0 12 0 6 12 0 6 12 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 42 0 0 0 0 0 0 % W
% Tyr: 0 12 0 0 0 0 0 12 0 6 0 0 6 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _