KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VARS
All Species:
28.48
Human Site:
Y753
Identified Species:
39.17
UniProt:
P26640
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26640
NP_006286.1
1264
140476
Y753
G
E
D
P
D
G
R
Y
W
V
S
G
R
N
E
Chimpanzee
Pan troglodytes
XP_001160008
1264
140384
Y753
G
E
D
P
D
G
R
Y
W
V
S
G
R
N
E
Rhesus Macaque
Macaca mulatta
Q5TM74
1064
118624
L623
L
E
T
G
S
D
L
L
L
F
W
V
G
R
M
Dog
Lupus familis
XP_538837
1256
139671
Y753
G
E
D
P
D
E
R
Y
W
V
S
G
R
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1Q9
1263
140197
Y752
G
E
D
P
D
G
R
Y
W
V
S
G
R
T
E
Rat
Rattus norvegicus
Q04462
1264
140350
Y753
G
E
D
P
D
G
R
Y
W
V
S
G
R
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520676
985
109386
R545
A
V
H
P
K
D
P
R
Y
Q
H
L
R
G
K
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088439
1243
140617
Y732
G
E
D
T
D
G
K
Y
W
I
S
G
R
S
E
Zebra Danio
Brachydanio rerio
XP_682807
1111
123867
V655
N
E
S
E
D
L
R
V
F
Y
P
G
T
L
L
Tiger Blowfish
Takifugu rubipres
P49696
1217
138200
Y700
G
E
D
M
D
G
H
Y
R
V
S
G
R
T
P
Fruit Fly
Dros. melanogaster
NP_524838
1049
118236
S609
L
Q
T
F
Y
P
T
S
L
L
E
T
G
H
D
Honey Bee
Apis mellifera
XP_395202
1043
121057
T603
F
E
A
F
Y
P
G
T
L
L
E
T
G
H
D
Nematode Worm
Caenorhab. elegans
Q9U1Q4
1050
118902
V610
H
D
I
L
F
F
W
V
A
R
M
V
F
M
A
Sea Urchin
Strong. purpuratus
XP_001200958
1119
126755
P669
P
D
L
Q
E
Y
Y
P
S
S
V
L
E
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93736
1108
125908
H656
T
S
V
L
E
T
G
H
D
I
L
F
F
W
V
Baker's Yeast
Sacchar. cerevisiae
P07806
1104
125751
Y655
T
K
D
M
E
T
F
Y
P
F
S
M
L
E
T
Red Bread Mold
Neurospora crassa
P28350
1093
123334
W653
T
S
M
L
E
T
G
W
D
I
L
F
F
W
V
Conservation
Percent
Protein Identity:
100
99.5
43.4
92.8
N.A.
93.4
93.4
N.A.
63
N.A.
65.3
45
63.8
50.9
49.1
44.9
44.4
Protein Similarity:
100
99.8
56
95.6
N.A.
96.4
96.3
N.A.
69.8
N.A.
78
58.8
76.8
63.1
63.4
59.5
59.6
P-Site Identity:
100
100
6.6
80
N.A.
93.3
93.3
N.A.
13.3
N.A.
73.3
26.6
66.6
0
6.6
0
0
P-Site Similarity:
100
100
6.6
93.3
N.A.
93.3
93.3
N.A.
26.6
N.A.
93.3
33.3
66.6
26.6
26.6
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.6
42.6
40.3
Protein Similarity:
N.A.
N.A.
N.A.
58.3
60.1
56
P-Site Identity:
N.A.
N.A.
N.A.
0
20
0
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
6
0
0
0
0
0
6
0
0
0
0
0
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
48
0
48
12
0
0
12
0
0
0
0
0
12
% D
% Glu:
0
59
0
6
24
6
0
0
0
0
12
0
6
6
30
% E
% Phe:
6
0
0
12
6
6
6
0
6
12
0
12
18
0
0
% F
% Gly:
42
0
0
6
0
36
18
0
0
0
0
48
18
6
6
% G
% His:
6
0
6
0
0
0
6
6
0
0
6
0
0
12
0
% H
% Ile:
0
0
6
0
0
0
0
0
0
18
0
0
0
0
0
% I
% Lys:
0
6
0
0
6
0
6
0
0
0
0
0
0
0
12
% K
% Leu:
12
0
6
18
0
6
6
6
18
12
12
12
6
6
6
% L
% Met:
0
0
6
12
0
0
0
0
0
0
6
6
0
6
6
% M
% Asn:
6
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% N
% Pro:
6
0
0
36
0
12
6
6
6
0
6
0
0
0
6
% P
% Gln:
0
6
0
6
0
0
0
0
0
6
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
36
6
6
6
0
0
48
6
0
% R
% Ser:
0
12
6
0
6
0
0
6
6
6
48
0
0
12
0
% S
% Thr:
18
0
12
6
0
18
6
6
0
0
0
12
6
24
6
% T
% Val:
0
6
6
0
0
0
0
12
0
36
6
12
0
0
12
% V
% Trp:
0
0
0
0
0
0
6
6
36
0
6
0
0
12
0
% W
% Tyr:
0
0
0
0
12
6
6
48
6
6
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _