KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CD27
All Species:
4.55
Human Site:
S219
Identified Species:
12.5
UniProt:
P26842
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26842
NP_001233.1
260
29137
S219
H
Q
R
R
K
Y
R
S
N
K
G
E
S
P
V
Chimpanzee
Pan troglodytes
XP_001157732
239
25988
L199
L
A
L
T
S
T
A
L
L
F
L
L
F
F
L
Rhesus Macaque
Macaca mulatta
XP_001104258
260
29211
S219
H
Q
Q
R
K
Y
R
S
N
K
G
E
S
P
M
Dog
Lupus familis
XP_854464
271
30482
L230
H
Q
Q
R
K
Y
R
L
N
K
E
E
Y
P
V
Cat
Felis silvestris
Mouse
Mus musculus
P41272
250
28145
G209
F
H
Q
R
R
N
H
G
P
N
E
D
R
Q
A
Rat
Rattus norvegicus
P15725
271
29877
L229
L
L
A
P
L
T
V
L
L
A
L
Y
L
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507233
101
11103
P61
N
S
K
C
G
C
Q
P
G
L
Q
C
Q
D
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084466
328
37234
L258
W
D
Q
F
M
R
N
L
H
I
S
A
N
T
V
Zebra Danio
Brachydanio rerio
NP_001035459
200
21452
G160
T
K
S
S
C
P
D
G
Y
K
L
K
K
G
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
21.5
93.8
70.1
N.A.
64.2
25.4
N.A.
21.1
N.A.
21.6
20.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
35.7
95.3
77.4
N.A.
71.9
36.5
N.A.
28.4
N.A.
32.3
36.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
86.6
73.3
N.A.
6.6
0
N.A.
0
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
80
N.A.
26.6
0
N.A.
20
N.A.
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
12
0
0
0
12
0
0
12
0
12
0
0
12
% A
% Cys:
0
0
0
12
12
12
0
0
0
0
0
12
0
0
0
% C
% Asp:
0
12
0
0
0
0
12
0
0
0
0
12
0
12
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
23
34
0
0
0
% E
% Phe:
12
0
0
12
0
0
0
0
0
12
0
0
12
12
0
% F
% Gly:
0
0
0
0
12
0
0
23
12
0
23
0
0
12
0
% G
% His:
34
12
0
0
0
0
12
0
12
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% I
% Lys:
0
12
12
0
34
0
0
0
0
45
0
12
12
0
0
% K
% Leu:
23
12
12
0
12
0
0
45
23
12
34
12
12
12
12
% L
% Met:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
12
% M
% Asn:
12
0
0
0
0
12
12
0
34
12
0
0
12
0
12
% N
% Pro:
0
0
0
12
0
12
0
12
12
0
0
0
0
34
0
% P
% Gln:
0
34
45
0
0
0
12
0
0
0
12
0
12
12
12
% Q
% Arg:
0
0
12
45
12
12
34
0
0
0
0
0
12
0
12
% R
% Ser:
0
12
12
12
12
0
0
23
0
0
12
0
23
0
0
% S
% Thr:
12
0
0
12
0
23
0
0
0
0
0
0
0
12
0
% T
% Val:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
34
% V
% Trp:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
34
0
0
12
0
0
12
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _